Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,973 questions · 3,072 findings · 410 reviews · Headline outcomes only

No studies found 559 · 18.2%GRADE not reported 143 · 4.7%Very low 654 · 21.3%Low 833 · 27.1%Moderate 683 · 22.2%High 200 · 6.5%

Pharmacological treatment vs pharmacological treatment 2

All‐cause mortality ‐ short term (end of treatment) · health problem or population

It is very uncertain whether summary of findings table ‐ Pharmacological treatment 1 changes all‐cause mortality ‐ short term (end of treatment) compared with pharmacological treatment 2 (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Psychological interventions vs control

All‐cause mortality ‐ short‐term · health problem or population

It is very uncertain whether summary of findings table ‐ Psychological treatment changes all‐cause mortality ‐ short‐term compared with control (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Psychological interventions vs control

Cardiovascular mortality · health problem or population

Summary of findings table ‐ Psychological treatment showed no clear difference in cardiovascular mortality ‐ long‐term compared with control; GRADE not reported.

1 finding from 1 review

Psychological interventions vs psychological treatment

Depression remission · health problem or population

Summary of findings table ‐ Psychological treatment 1 showed no clear difference in depression remission ‐ short term (end of treatment) compared with psychological treatment 2 (low certainty).

1 finding from 1 review