Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,327 questions · 2,494 findings · 87 reviews · Oral Health

No studies found 450 · 18%GRADE not reported 1,487 · 59.6%Very low 385 · 15.4%Low 121 · 4.9%Moderate 50 · 2%High 1 · 0%

Hyperbaric oxygen vs No HBO therapy

Implant failure · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

Hyperbaric oxygen (HBO) therapy showed no clear difference in implant failure compared with no HBO therapy; GRADE not reported.

1 finding from 1 review

Hyperbaric oxygen vs No HBO therapy

Postimplantation complications · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

Hyperbaric oxygen (HBO) therapy showed no clear difference in postimplantation complications compared with no HBO therapy; GRADE not reported.

1 finding from 1 review

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Implant failure · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) probably leads to lower implant failure compared with no antibiotics or placebo (moderate certainty).

1 finding from 1 review

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Adverse events · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in adverse events compared with no antibiotics or placebo; GRADE not reported.

1 finding from 1 review

Implant surface smoothening added to systemic antibiotics + resective surgery + local antibiotics vs No implant surface smoothening (same surgical protocol)

Implant failure · People with at least one dental implant affected by perimplantitis

Implant surface smoothening added to systemic antibiotics +… showed no clear difference in implant failure compared with no implant surface smoothening (same surgical protocol); GRADE not reported.

1 finding from 1 review

Radix tripterygium hypoglaucum tablet (THT) vs Tripterygium glucosides tablet (TGT)

Partial response (remarkably effective or effective) · People with erosive oral lichen planus

Radix tripterygium hypoglaucum tablet (THT) led to lower partial response (remarkably effective or effective) compared with tripterygium glucosides tablet (TGT); GRADE not reported.

2 findings from 1 review

Topical clobetasol propionate 0.025% vs clobetasol cream 0.05% cream

Physician Global Assessment (Thongprasom score) · People with erosive oral lichen planus

Topical clobetasol propionate 0.025% showed no clear difference in physician Global Assessment (Thongprasom score) compared with topical clobetasol propionate 0.05%; GRADE not reported.

1 finding from 1 review

Low-gold (Midas) or silver-palladium (Albacast) alloy FDP vs High-gold content control alloy (JS C) FDP

Visual marginal discrepancy (3 years) · Patients receiving single crowns and FDPs; split-mouth

Low-gold (Midas) or silver-palladium (Albacast) alloy FDP showed no clear difference in visual marginal discrepancy (3 years) compared with high-gold content control alloy (JS C) FDP; GRADE not reported.

1 finding from 1 review

Glucosamine sulfate (oral) vs ibuprofen

Maximum voluntary jaw opening (mm), change from baseline · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

Glucosamine sulfate (oral) showed no clear difference in maximum voluntary jaw opening (mm), change from baseline compared with ibuprofen (oral); GRADE not reported.

1 finding from 1 review

Fixed dental prosthesis (cantilever FDP) vs Removable dental prosthesis (RDP)

Incidence-free survival (caries, endodontic treatment, tooth loss) · Patients with a shortened dental arch (missing posterior teeth)

Fixed dental prosthesis (cantilever FDP) showed no clear difference in incidence-free survival (caries, endodontic treatment, tooth loss) compared with removable dental prosthesis (RDP); GRADE not reported.

1 finding from 1 review