Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,696 questions · 3,815 findings · 855 reviews

No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Usual care with ivabradine vs Placebo, no intervention or usual care (with or without placebo)

Number of days spent in hospital due to heart failure during · adults (≥ 18 years of age) with a diagnosis of chronic heart failure with reduced ejection fraction (HFrEF)

The review found no eligible studies for this question.

2 findings from 1 review

Usual care with ivabradine vs Placebo, no intervention or usual care (with or without placebo)

Number of days spent in hospital due to heart failure during · patients with chronic heart failure with preserved ejection fraction

The review found no eligible studies for this question.

2 findings from 1 review

Advance care planning vs usual care

Concordance between participants' preferences and end‐of‐life care (yes/no) Post‐death data: mean days to death, ACP group (388.8 ± 255.7); usual care group (362.2 ± 288.4) · people with heart failure with or without their surrogate decision‐makers/carers

It is very uncertain whether advance care planning changes concordance between participants' preferences and end‐of‐life care… compared with usual care (very low certainty).

1 finding from 1 review

Transverse groin incision vs vertical groin incision

Lymphatic complications: Lymphatic leak (28 days) Lymphatic collection (28 days) · patients undergoing surgery with femoral artery approach

It is very uncertain whether transverse groin incision changes lymphatic complications: Lymphatic leak (28 days) Lymphatic… compared with vertical groin incision (very low certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Surgical site infections: liver transplant recipients Time frame: 30 days · solid organ transplant recipients

It is very uncertain whether extended changes surgical site infections: liver transplant recipients Time frame: 30… compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Graft loss including death · solid organ transplant recipients

It is very uncertain whether extended changes graft loss (including death with functioning graft) Time frame: 30… compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Other infection: septicaemia Time frame: 2 to 6 weeks · solid organ transplant recipients

It is very uncertain whether extended changes other infection: septicaemia Time frame: 30 days compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Other infection: pneumonia Time frame: 30 days · solid organ transplant recipients

It is very uncertain whether extended changes other infection: pneumonia Time frame: 30 days compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Surgical site infections: kidney transplant recipients Time frame: 30 days · solid organ transplant recipients

It is very uncertain whether extended changes surgical site infections: kidney transplant recipients Time frame:… compared with short duration antibiotics (very low certainty).

1 finding from 1 review