Stroke · adult patients with hypertension
Lower BP target showed no clear difference in stroke№ of participants: 37,087(7 RCTs) compared with standard BP target (low certainty).
1 finding from 1 review
RR 0.88 [0.77, 1.01]
Studies not reported
Low
Congestive heart failure · adult patients with hypertension
Lower BP target may leads to lower congestive heart failure№ of participants: 15,859(5 RCTs) compared with standard BP target (low certainty).
1 finding from 1 review
RR 0.75 [0.6, 0.92]
Studies not reported
Low
Other serious adverse events · adult patients with hypertension
Lower BP target may leads to higher other serious adverse events compared with standard BP target (low certainty).
1 finding from 1 review
RR 1.44 [1.32, 1.59]
Studies not reported
Low
24‐h ambulatory systolic BP · hyperuricaemia in people with hypertension
1 finding from 1 review
24‐h ambulatory diastolic BP · hyperuricaemia in people with hypertension
1 finding from 1 review
Systolic blood pressure · hyperuricaemia in people with hypertension
1 finding from 1 review
Diastolic blood pressure · hyperuricaemia in people with hypertension
1 finding from 1 review
Serum UA · hyperuricaemia in people with hypertension
1 finding from 1 review
Withdrawals due to adverse events · hyperuricaemia in people with hypertension
Uric acid‐lowering drug showed no clear difference in adverse events (withdrawals due to side effects) compared with placebo (low certainty).
1 finding from 1 review
Total mortality · people with primary hypertension
It is very uncertain whether combination therapy changes total mortality compared with monotherapy (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · people with primary hypertension
1 finding from 1 review
Cardiovascular mortality · people with primary hypertension
1 finding from 1 review
Cardiovascular events · people with primary hypertension
It is very uncertain whether combination therapy changes cardiovascular events compared with monotherapy (very low certainty).
1 finding from 1 review
Serious adverse events · people with primary hypertension
It is very uncertain whether combination therapy changes serious adverse events compared with monotherapy (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · people with primary hypertension
It is very uncertain whether combination therapy changes withdrawals due to adverse effects compared with monotherapy (very low certainty).
1 finding from 1 review
Total mortality · people with primary hypertension
It is very uncertain whether combination with potassium‐sparing diuretics changes total mortality compared with monotherapy (very low certainty).
1 finding from 1 review
Cardiovascular mortality · people with primary hypertension
1 finding from 1 review
Cardiovascular events · people with primary hypertension
It is very uncertain whether combination with potassium‐sparing diuretics changes cardiovascular events compared with monotherapy (very low certainty).
1 finding from 1 review
Serious adverse events · people with primary hypertension
It is very uncertain whether combination with potassium‐sparing diuretics changes serious adverse events compared with monotherapy (very low certainty).
1 finding from 1 review
All‐cause mortality · people with primary hypertension
Renin inhibitors showed no clear difference in all‐cause mortality compared with ACE inhibitors (low certainty).
1 finding from 1 review