Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,751 questions · 12,775 findings · 807 reviews · Headline outcomes only

No studies found 3,413 · 26.7%GRADE not reported 709 · 5.5%Very low 3,483 · 27.3%Low 3,165 · 24.8%Moderate 1,628 · 12.7%High 377 · 3%

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Mild clobetasol propionate cream regimen (10 to 30 g/day) vs standard clobetasol propionate cream regimen (40 g/day)

Adverse events at 1 year · bullous pemphigoid

Mild clobetasol propionate cream regimen (10 to 30 g/day) showed no clear difference in adverse events at 1 year compared with standard clobetasol propionate cream regimen (40 g/day) (low certainty).

1 finding from 1 review

Doxycycline vs prednisolone

Disease control · bullous pemphigoid

Doxycycline leads to lower disease control at 6 weeks (unadjusted raw data) compared with prednisolone (high certainty).

1 finding from 1 review

An intervention in which one's attention is on the experience of stress (feelings, thoughts, behavior) vs no intervention/wait list/placebo/no stress‐reduction intervention

Stress symptoms ( · healthcare workers
3 findings from 1 review

An intervention in which one's attention is away from the experience of stress vs no intervention/wait list/placebo/no stress‐reduction intervention

Stress symptoms ( · healthcare workers
3 findings from 1 review

An intervention in which the focus is on work‐related risk factors on an individual level vs no intervention/no stress‐reduction interventionfor stress reduction

Stress symptoms ( · healthcare workers
3 findings from 1 review

Summary of findings table ‐ Anger management vs waiting list control

Aggressive behaviour: severity of incidents: Aberrant Behaviour Checklist (ABC – irritability subscale – key worker report – post‐treatment (Analysis 1.2.1) · outwardly aggressive behaviour in people with intellectual disability
1 finding from 1 review

Summary of findings table ‐ Positive behavioural support vs treatment

Mental state: Common Mental Disorder (CMD) – at 6 months (Analysis 2.2.1) (CMD) · outwardly aggressive behaviour in people with intellectual disability

Summary of findings table ‐ Positive behavioural support showed no clear difference in mental state: Common Mental Disorder (CMD) – at 6 months (Analysis… compared with treatment (low certainty).

1 finding from 1 review

Summary of findings table ‐ Mindfulness based on positive behaviour support vs positive behaviour support

Aggressive behaviour: aggressive events – carer reports – post‐training (Analysis 4.1) · outwardly aggressive behaviour in people with intellectual disability
1 finding from 1 review

Summary of findings table ‐ Anger management vs waiting list control

Ability to control anger: Provocation Inventory (PI) ‐ self report: Post‐treatment (scale range 0 to 75; higher scores indicate higher levels of aggression) · outwardly aggressive behaviour in people with intellectual disability
1 finding from 1 review

Summary of findings table ‐ Mindfulness based on positive behaviour support vs positive behaviour support

Ability to control anger ‐ not measured · outwardly aggressive behaviour in people with intellectual disability

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Mindfulness based on positive behaviour support vs positive behaviour support

Adaptive functioning ‐ not measured · outwardly aggressive behaviour in people with intellectual disability

The review found no eligible studies for this question.

1 finding from 1 review