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What do systematic reviews say?

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Evidence found and GRADE certainty

1,655 questions · 1,751 findings · 147 reviews · Pain, Palliative and Supportive Care

No studies found 361 · 20.6%GRADE not reported 87 · 5%Very low 625 · 35.7%Low 367 · 21%Moderate 232 · 13.2%High 79 · 4.5%

Intervention not reported

Pain end of treatment (0‐10 scale) Higher scores indicate higher pain levels · Patients with fibromyalgia
1 finding from 1 review

Intervention not reported

Negative mood end of treatment (0‐10 scale) Higher scores indicate higher negative mood levels · Patients with fibromyalgia
1 finding from 1 review

Intervention not reported

Disability end of treatment (0‐10 scale) Higher scores indicate disability levels · Patients with fibromyalgia
1 finding from 1 review

Intervention not reported

Acceptability end of treatment (dropouts from study due to any reasons) · Patients with fibromyalgia

The intervention showed no clear difference in acceptability end of treatment (dropouts from study due to any… (low certainty).

1 finding from 1 review

Pregabalin vs placebo at end of treatment

Patient Global Impression of Change much or very much improved · patients with fibromyalgia

Pregabalin leads to higher patient Global Impression of Change of 'much' or 'very much' improved compared with placebo at end of treatment (high certainty).

1 finding from 1 review