What do systematic reviews say?

Exercise vs usual care

• Exercise therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 53 participants
  Low

Exercise vs usual care

• Exercise therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 83 participants
  Very low

Exercise vs usual care

• Exercise therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 123 participants
  Very low

Exercise vs usual care

• Exercise therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 136 participants
  Very low

Exercise vs usual care

• Exercise therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 331 participants
  Low

Exercise vs usual care

It is very uncertain whether exercise therapies changes adherence to aromatase inhibitors compared with standard care (very low certainty).

• Exercise therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2020 · Cochrane Headline outcomes only
  OR 2.43 [0.41, 14.63]
  2 studies · 224 participants
  Very low

Intervention not reported

The review found no eligible studies for this question.

• Health education interventions to promote early presentation and referral for women with symptoms of endometrial cancer 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Health education interventions to promote early presentation and referral for women with symptoms of endometrial cancer 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Health education interventions to promote early presentation and referral for women with symptoms of endometrial cancer 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Health education interventions to promote early presentation and referral for women with symptoms of endometrial cancer 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Health education interventions to promote early presentation and referral for women with symptoms of endometrial cancer 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Health education interventions to promote early presentation and referral for women with symptoms of endometrial cancer 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

12,500 ppm F (NaF/olaflur/dectaflur) amine fluoride gel vs Placebo gel

The review found no eligible studies for this question.

• Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes

  At debond (end of orthodontic treatment)
  Additional SoF Table 1. Number of participants with more severe DLs: none of the trials reported this outcome.
  0 studies
  No studies found

Patient-used 5000 ppm F toothpaste, daily vs 1450 to 1500 ppm F toothpaste

The review found no eligible studies for this question.

• Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes

  At debond (end of orthodontic treatment)
  SoF 3. Number of participants with more severe DLs: none of the trials reported this outcome.
  0 studies
  No studies found

1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily vs 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily

The review found no eligible studies for this question.

• Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes

  At debond (end of orthodontic treatment)
  Additional SoF Table 2. Number of participants with more severe DLs: none of the trials reported this outcome.
  0 studies
  No studies found

1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily vs 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily

The review found no eligible studies for this question.

• Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes

  At debond (end of orthodontic treatment)
  Additional SoF Table 2. Adverse effects: none of the trials reported this outcome.
  0 studies
  No studies found

Slow-release fluoride device (fluoride glass beads) vs Fluoride mouthrinse

The review found no eligible studies for this question.

• Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes

  At debond (end of orthodontic treatment)
  Additional SoF Table 3. Number of participants with more severe DLs: none of the trials reported this outcome.
  0 studies
  No studies found

1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily vs 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily

It is very uncertain whether 1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily changes gingival bleeding index (mean change from baseline) compared with 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily (very low certainty).

• Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes

  At debond; follow-up 1.5 years
  MD -0.07 [-0.15, 0.01]
  1 study · 97 participants
  Very low

1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily vs 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily

It is very uncertain whether 1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily changes white spot lesion index (mean change from baseline) compared with 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily (very low certainty).

• Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes

  At debond; follow-up 1.5 years
  MD -0.05 [-0.10, 0]
  1 study · 97 participants
  Very low

Fluoride varnish vs Non-fluoride (placebo) varnish

Professionally-applied fluoride varnish (7700 or 10,000 ppm F),… showed no clear difference in number of participants with new demineralised lesions (DLs) compared with non-fluoride (placebo) varnish (low certainty).

• Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes

  At debond; follow-up 1.7 years
  RR 0.52 [0.14, 1.93]
  2 studies · 405 participants
  Low