Findings

What do systematic reviews say?

2,123 questions · 2,188 findings · 243 reviews

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No studies found 493 · 22.5%GRADE not reported 160 · 7.3%Very low 600 · 27.4%Low 474 · 21.7%Moderate 364 · 16.6%High 97 · 4.4%

Clindamycin plus aminoglycoside vs regimens containing cephalosporin

Length of stay · women with PID

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for pelvic inflammatory disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Clindamycin plus aminoglycoside vs regimens containing cephalosporin

Fertility outcome · women with PID

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for pelvic inflammatory disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Regimens containing macrolides (azithromycin) vs regimens containing tetracycline (doxycycline)

Microbiological clearance · women with PID

Regimens containing macrolides (azithromycin) showed no clear difference in microbiological clearance compared with regimens containing tetracycline (doxycycline); GRADE not reported.

1 finding from 1 review

Antibiotic therapy for pelvic inflammatory disease 2020 · Cochrane Headline outcomes only
RR 1.02 [0.98, 1.06]
Studies not reported
GRADE not reported

Regimens containing macrolides (azithromycin) vs regimens containing tetracycline (doxycycline)

Laparoscopic evidence of resolution of PID based on physician opinion · women with PID

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for pelvic inflammatory disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Regimens containing macrolides (azithromycin) vs regimens containing tetracycline (doxycycline)

Length of stay · women with PID

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for pelvic inflammatory disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Regimens containing macrolides (azithromycin) vs regimens containing tetracycline (doxycycline)

Fertility outcome · women with PID

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for pelvic inflammatory disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Regimens containing quinolone vs regimens containing cephalosporin

Clinical cure according to criteria established by study authors Mild‐moderate PID · women with PID

Regimens containing quinolone showed no clear difference in clinical cure according to criteria established by study authors… compared with regimens containing cephalosporins (low certainty).

1 finding from 1 review

Antibiotic therapy for pelvic inflammatory disease 2020 · Cochrane Headline outcomes only
RR 1.05 [0.98, 1.14]
Studies not reported
Low

Intervention not reported

Health‐related quality of life · CSOM, recurrence of CSOM or suppuration following mastoidectomy or tympanoplasty

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Ear pain (otalgia) or discomfort or local irritation · CSOM, recurrence of CSOM or suppuration following mastoidectomy or tympanoplasty

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Hearing · CSOM, recurrence of CSOM or suppuration following mastoidectomy or tympanoplasty

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Serious complications · CSOM, recurrence of CSOM or suppuration following mastoidectomy or tympanoplasty

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Suspected ototoxicity · CSOM, recurrence of CSOM or suppuration following mastoidectomy or tympanoplasty

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 190 participants
Very low

Quinolone vs aminoglycosides

Resolution of ear discharge ‐ measured at 1 to 2 weeks · people (of any age) with CSOM

It is very uncertain whether quinolones changes resolution of ear discharge ‐ measured at 1 to 2 weeks compared with aminoglycosides (very low certainty).

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
RR 1.95 [0.88, 4.29]
6 studies · 694 participants
Very low

Quinolone vs aminoglycosides

Resolution of ear discharge ‐ measured after 4 weeks · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Quinolone vs aminoglycosides

Health‐related quality of life · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Quinolone vs aminoglycosides

Ear pain (otalgia) or discomfort or local irritation · people (of any age) with CSOM

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 308 participants
Very low

Quinolone vs aminoglycosides

Hearing · people (of any age) with CSOM

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 132 participants
Very low

Quinolone vs aminoglycosides

Serious complications · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Quinolone vs aminoglycosides

Suspected ototoxicity · people (of any age) with CSOM

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 352 participants
Very low

Intervention not reported

Resolution of ear discharge‐ measured at 1 to 2 weeks · CSOM, recurrence of CSOM or suppuration following mastoidectomy or tympanoplasty

The intervention may leads to higher resolution of ear discharge‐ measured at 1 to 2 weeks (low certainty).

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
RR 1.47 [1.2, 1.8]
2 studies · 150 participants
Low