Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Intervention not reported

Activity limitations 100‐point Disabilities of the Arm, Shoulder and Hand questionnaire (lower score reflects better outcome) · people with non‐neurological conditions1
1 finding from 1 review

Intervention not reported

Pain 10‐point VAS (lower score reflects better outcome) · people with neurological conditions1
1 finding from 1 review

Intervention not reported

Pain 10‐point VAS (lower score reflects better outcome) · people with non‐neurological conditions1
1 finding from 1 review

Intervention not reported

NIPS ‐ Proportion of infants in low or no pain during procedure · procedural pain in neonates
1 finding from 1 review

Intervention not reported

Duration of cry (seconds) following heel lance · procedural pain in neonates
1 finding from 1 review

Intervention not reported

Duration of cry (seconds) following IM injection · procedural pain in neonates
1 finding from 1 review

Intervention not reported

Difficult tracheal intubation: low risk of bias trials · improving conditions during tracheal intubation or direct laryngoscopy in adults and adolescents

The intervention probably leads to higher difficult tracheal intubation: low risk of bias trials (moderate certainty).

1 finding from 1 review

Intervention not reported

One or more events of upper airway discomfort or injury: low risk of bias trials · improving conditions during tracheal intubation or direct laryngoscopy in adults and adolescents

The intervention led to higher one or more events of upper airway discomfort or injury: low risk of…; GRADE not reported.

1 finding from 1 review

Intervention not reported

Difficult laryngoscopy: low risk of bias trials · improving conditions during tracheal intubation or direct laryngoscopy in adults and adolescents

The intervention showed no clear difference in difficult laryngoscopy: low risk of bias trials; GRADE not reported.

1 finding from 1 review

Summary of findings table ‐ Silicone earplugs vs no earplugs

Cerebral palsy · preterm or very low birth weight infants

It is very uncertain whether summary of findings table ‐ Silicone earplugs changes cerebral palsy at 18 to 22 months' corrected age compared with no earplugs (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Silicone earplugs vs no earplugs

Normal auditory functioning at discharge · preterm or very low birth weight infants

It is very uncertain whether summary of findings table ‐ Silicone earplugs changes normal auditory functioning at discharge compared with no earplugs (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Silicone earplugs vs no earplugs

All‐cause mortality during hospital stay · preterm or very low birth weight infants

It is very uncertain whether summary of findings table ‐ Silicone earplugs changes all‐cause mortality during hospital stay compared with no earplugs (very low certainty).

1 finding from 1 review