Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,661 questions · 2,751 findings · 453 reviews

No studies found 593 · 21.6%GRADE not reported 277 · 10.1%Very low 538 · 19.6%Low 712 · 25.9%Moderate 516 · 18.8%High 115 · 4.2%

Dexmedetomidine vs traditional sedative agents

Bradycardia · Critically ill patients requiring long‐term sedation during mechanical ventilation

It is very uncertain whether dexmedetomidine changes incidence of bradycardia compared with traditional sedative agents (very low certainty).

1 finding from 1 review

Dexmedetomidine vs traditional sedative agents

All‐cause mortality · Critically ill patients requiring long‐term sedation during mechanical ventilation

It is very uncertain whether dexmedetomidine changes mortality compared with traditional sedative agents (very low certainty).

1 finding from 1 review

Silver alloyed catheter vs silicone catheter

urinary tract infections Bacterial biofilm on the surfaces of catheters. UTI was defined as uropathogenic colonisation of urinary catheter. · patients with long‐term bladder drainage in adults

Silver alloyed catheter showed no clear difference in urinary tract infections Bacterial biofilm on the surfaces of… compared with silicone catheter (low certainty).

1 finding from 1 review

Latex catheter vs silicone catheter

retaining catheter for less than 6 weeks procedure not specified · patients with long‐term bladder drainage in adults

Latex catheter showed no clear difference in retaining catheter for less than 6 weeks procedure not specified compared with silicone catheter (moderate certainty).

1 finding from 1 review

Latex catheter vs silicone catheter

pain, bleeding or purulent discharge procedure not specified · patients with long‐term bladder drainage in adults

Latex catheter showed no clear difference in pain, bleeding or purulent discharge procedure not specified compared with silicone catheter (moderate certainty).

1 finding from 1 review