Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,751 questions · 12,775 findings · 807 reviews · Headline outcomes only

No studies found 3,413 · 26.7%GRADE not reported 709 · 5.5%Very low 3,483 · 27.3%Low 3,165 · 24.8%Moderate 1,628 · 12.7%High 377 · 3%

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Test‐based attendance vs routine isolation after contact with a SARS‐CoV‐2 positive person

COVID‐related absenteeism from work Days absent per 1000 working days (over 13‐week · school staff

Test‐based attendance showed no clear difference in COVID‐related absenteeism from work Days absent per 1000 working… compared with routine isolation after contact with a SARS‐CoV‐2‐positive person (low certainty).

1 finding from 1 review

Summary of findings table ‐ High sodium dialysate vs standard sodium dialysate

Dialysis dysequilibrium syndrome · patients requiring haemodialysis

It is very uncertain whether summary of findings table ‐ High sodium dialysate changes dialysis dysequilibrium syndrome compared with standard sodium dialysate (very low certainty).

1 finding from 1 review

Summary of findings table ‐ High sodium dialysate vs standard sodium dialysate

Severe dialysis dysequilibrium syndrome · patients requiring haemodialysis

It is very uncertain whether summary of findings table ‐ High sodium dialysate changes severe dialysis dysequilibrium syndrome compared with standard sodium dialysate (very low certainty).

1 finding from 1 review

Clobetasol propionate cream vs prednisone

Disease control (healing of skin lesions) at day 21 · bullous pemphigoid

Clobetasol propionate cream probably leads to higher disease control (healing of skin lesions) at day 21 compared with oral prednisone (moderate certainty).

1 finding from 1 review

Doxycycline vs prednisolone

Treatment‐related mortality at 1 year (mITT) · bullous pemphigoid

Doxycycline probably leads to lower treatment‐related mortality at 1 year (mITT) compared with prednisolone (moderate certainty).

1 finding from 1 review