Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,454 questions · 3,562 findings · 816 reviews · Headline outcomes only

No studies found 538 · 15.1%GRADE not reported 239 · 6.7%Very low 933 · 26.2%Low 1,041 · 29.2%Moderate 612 · 17.2%High 199 · 5.6%

5‐ASA vs control

Incisional infections and wound dehiscence within 30 days of surgery · people with inflammatory bowel disease

Risk of postoperative infectious complications: 5‐ASA led to lower incisional infections and wound dehiscence within 30 days of surgery compared with control; GRADE not reported.

1 finding from 1 review

5‐ASA vs control

Intra‐abdominal infectious complications within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: 5‐ASA changes intra‐abdominal infectious complications within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: immunomodulators vs control

Infectious complications · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: immunomodulators changes overall infectious complications within 30 days of surgery compared with control (very low certainty).

3 findings from 1 review

Risk of postoperative infectious complications: immunomodulators vs control

Incisional infections and wound dehiscence within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: immunomodulators changes incisional infections and wound dehiscence within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: immunomodulators vs control

Intra‐abdominal infectious complications within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: immunomodulators changes intra‐abdominal infectious complications within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: immunomodulators vs control

Extra‐abdominal infections within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: immunomodulators changes extra‐abdominal infections within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐TNF agents vs control

Infectious complications · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐TNF agents changes overall infectious complications within 30 days of surgery compared with control (very low certainty).

3 findings from 1 review

Risk of postoperative infectious complications: anti‐TNF agents vs control

Incisional infections and wound dehiscence within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐TNF agents changes incisional infections and wound dehiscence within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐TNF agents vs control

Intra‐abdominal infectious complications within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐TNF agents changes intra‐abdominal infectious complications within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐TNF agents vs control

Extra‐abdominal infections within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐TNF agents changes extra‐abdominal infections within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐integrin agents vs control

Infectious complications · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐integrin agents changes overall infectious complications within 30 days of surgery compared with control (very low certainty).

3 findings from 1 review

Risk of postoperative infectious complications: anti‐integrin agents vs control

Incisional infections and wound dehiscence within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐integrin agents changes incisional infections and wound dehiscence within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐integrin agents vs control

Intra‐abdominal infectious complications within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐integrin agents changes intra‐abdominal infectious complications within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐integrin agents vs control

Extra‐abdominal infections within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐integrin agents changes extra‐abdominal infections within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Corticosteroids vs control

Incisional infections and wound dehiscence within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: corticosteroids changes incisional infections and wound dehiscence within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Corticosteroids vs control

Intra‐abdominal infectious complications within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: corticosteroids changes intra‐abdominal infectious complications within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Corticosteroids vs control

Extra‐abdominal infections within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: corticosteroids changes extra‐abdominal infections within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

5‐ASA vs control

Infectious complications · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: 5‐ASA changes overall infectious complications within 30 days of surgery compared with control (very low certainty).

3 findings from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Mastectomy skin flap necrosis (number of women with mastectomy skin flap necrosis within 30 days after surgery) · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes mastectomy skin flap necrosis (number of women with mastectomy skin… compared with clinical evaluation (very low certainty).

1 finding from 1 review