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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

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No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Mechanical (high-volume) irrigation vs Manual (low-volume) irrigation

Presence of dry socket · Adults with mandibular third molars requiring removal

It is very uncertain whether mechanical (high-volume) irrigation changes alveolar osteitis compared with manual (low-volume) irrigation (very low certainty).

1 finding from 1 review

Clinical examination with risk-based recall vs Clinical examination with 24-month recall

Dental caries · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in dental caries: number of tooth surfaces with any caries (ICDAS 1-6) compared with clinical examination with 24-month recall (moderate certainty).

1 finding from 1 review

Audiovisual distraction vs Conventional treatment

Adverse effects: pain on injection (solution deposition), Heft-Parker VAS 0-170 mm · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

Audiovisual distraction showed no clear difference in pain on injection (Wong-Baker Faces Pain Rating Scale, after… compared with conventional treatment; GRADE not reported.

1 finding from 1 review

Laser fluorescence (LF; DIAGNOdent) vs Reference standard: histology (in vitro studies) or visual-tactile examination (in vivo studies)

Sensitivity · Adults presenting asymptomatically or suspected of having root caries (in vivo studies); extracted teeth of adults (in vitro studies). 2…
1 finding from 1 review
  • Tests to detect and inform the diagnosis of root caries 2020 · Cochrane All outcomes
    4 studies (4997 root surfaces) investigated laser fluorescence and reported estimates of sensitivity ranging from 0.50 to 0.81 and specificity ranging from 0.40 to 0.80. 2 studies evaluated tests on in vivo primary…
    4 studies
    Very low

Video modelling acclimatisation vs Acclimatisation in clinic (tell-show-do)

Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

The wand (computer-controlled LA delivery system) vs Sleeper One (electronic LA delivery system)

Adverse effects: pain on injection (solution deposition), Heft-Parker VAS 0-170 mm · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The wand (computer-controlled LA delivery system) showed no clear difference in pain on injection (self-reported; FACES Pain Scale Revised) compared with sleeper One (electronic LA delivery system); GRADE not reported.

1 finding from 1 review

All fluorescence-based devices (red, blue, and green fluorescence combined) vs Reference standard (histology, excavation, or enhanced visual examination)

Diagnostic odds ratio (DOR) by subgroup: Proximal surfaces (detection of early enamel caries, D1 threshold) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review

Any antimicrobial mouthwash and/or nasal spray (alone or in combination), at any concentration, delivered to the patient or HCW before and/or after an AGP vs No treatment or saline or water

COVID-19 viral content of aerosol · Patients without suspected or confirmed COVID-19 infection undergoing aerosol-generating procedures (AGPs), and the healthcare workers…

The review found no eligible studies for this question.

1 finding from 1 review

Piezoelectric bone removal vs Conventional rotary handpiece

Trismus / maximum mouth opening (mean) · Adults with mandibular third molars requiring removal

Piezoelectric bone removal led to higher trismus / maximum mouth opening (mean) compared with conventional rotary handpiece; GRADE not reported.

1 finding from 1 review

Rubber dam + HVE vs Cotton roll + HVE

Reduction in level of contamination in aerosols (CFU) during restorative procedures at participant's chest · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether rubber dam + HVE changes reduction in level of contamination in aerosols (CFU) during… compared with cotton roll + HVE (very low certainty).

1 finding from 1 review

Autologous platelet concentrate (PRP/PRF) in socket vs No blood product (conventional)

Postoperative pain (mean) · Adults with mandibular third molars requiring removal

Autologous platelet concentrate (PRP/PRF) in socket showed no clear difference in postoperative pain (mean) compared with no blood product (conventional); GRADE not reported.

1 finding from 1 review

Clinical examination with risk-based recall vs Clinical examination with 24-month recall

Cost (patient perspective): total cost per patient (GBP) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall led to higher cost (patient perspective): total cost per patient (GBP) compared with clinical examination with 24-month recall; GRADE not reported.

1 finding from 1 review

The wand (computer-controlled LA delivery system) vs other local anaesthetic

Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics)

Duration of ICU stay · Critically ill adults receiving mechanical ventilation in ICU

It is very uncertain whether toothbrushing (with or without antiseptics), as part of oral hygiene… changes duration of ICU stay compared with no toothbrushing (with or without antiseptics) (very low certainty).

1 finding from 1 review

High-volume evacuation (HVE) vs Conventional dental suction (low-volume evacuator / saliva ejector)

Reduction in level of contamination in aerosols (CFU) during ultrasonic scaling at 150 cm from mouth · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether high-volume evacuation (HVE) changes reduction in level of contamination in aerosols (CFU) during… compared with conventional dental suction (low-volume evacuator / saliva ejector) (very low certainty).

1 finding from 1 review