evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

4,667 questions · 21,760 findings · 2,177 reviews

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 4,173 · 19.2%GRADE not reported 2,300 · 10.6%Very low 5,276 · 24.2%Low 5,764 · 26.5%Moderate 3,298 · 15.2%High 949 · 4.4%

Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.

Traditional screening (referral card given if the inspecting dentist judges the child needs to see a dentist) vs No screening

Dental caries prevalence · School children (aged 4 to 15 years), primary and secondary schools in the UK and India
1 finding from 1 review
  • School dental screening programmes for oral health 2022 · Cochrane All outcomes
    Milsom 2006 measured prevalence of dental caries as mean number of teeth with active caries in primary teeth (dt) and permanent teeth (DT); post-intervention changes from baseline were not significant, and the authors…
    1 study · 16684 participants
    GRADE not reported

Double primary (canine and first molar) tooth extraction vs Single primary (canine) tooth extraction

Reported incidence or prevalence of root resorption of the impacted canine and/or incisors and/or first premolars · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

The review found no eligible studies for this question.

1 finding from 1 review

COE with vital rinsing (toluidine blue/tolonium chloride) vs Conventional oral examination (COE) alone

Detection rate of oral pre-malignant and malignant lesions after referral (COE+vital rinsing vs COE alone) · Oral cavity cancer or potentially malignant disorder symptom-free individuals with tobacco habits

COE with vital rinsing (toluidine blue/tolonium chloride) showed no clear difference in detection rate of oral pre-malignant and malignant lesions after… compared with conventional oral examination (COE) alone (moderate certainty).

1 finding from 1 review

Dornase alfa vs placebo or no dornase alfa treatment

FVC (% predicted) Change from baseline · adults and children with cystic fibrosis

Dornase alfa leads to higher relative mean percentage change in FVC (% predicted) at 6 months compared with placebo or no dornase alfa treatment (high certainty).

1 finding from 1 review