Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

358 questions · 403 findings · 68 reviews

No studies found 43 · 10.7%GRADE not reported 121 · 30%Very low 128 · 31.8%Low 66 · 16.4%Moderate 33 · 8.2%High 12 · 3%

Cooling treatment (ice pack) vs cooling treatment (cold gel pad)

Perineal bruising within 4 ‐ 6 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack) changes perineal bruising within 4 ‐ 6 hours of giving birth compared with cooling treatment (cold gel pad) (very low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs cooling treatment (cold gel pad)

Perineal bruising within 24 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack) changes perineal bruising within 24 hours of giving birth compared with cooling treatment (cold gel pad) (very low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs cooling treatment (cold gel pad)

Adverse effects on perineal wound healing: Day 5 ‐ Wound not healing · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack) changes adverse effects on perineal wound healing: Day 5 ‐ Wound not healing compared with cooling treatment (cold gel pad) (very low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs no treatment

Perineal pain 24 ‐ 48 hours after giving birth ‐ Moderate + severe pain · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack or cold gel pad) changes perineal pain between 24 ‐ 48 after giving birth ‐ Moderate + severe… compared with no treatment (very low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs cooling treatment (cold gel pad)

Adverse effects on perineal wound healing: Day 5 ‐ Wound edges gaping · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack) changes adverse effects on perineal wound healing: Day 5 ‐ Wound edges gaping compared with cooling treatment (cold gel pad) (very low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs cooling treatment (cold gel pad)

Maternal views and experiences with treatment ‐ Opinion on treatment effects (good + very good + excellent) Day 5 · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack) changes maternal views and experiences with treatment ‐ Opinion on treatment… compared with cooling treatment (cold gel pad) (very low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs cooling treatment (cold gel pad)

Maternal views and experiences of treatment ‐ Satisfaction with overall perineal care (good + very good + excellent) Day 10 · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack) changes maternal views and experiences with treatment ‐ Satisfaction with… compared with cooling treatment (cold gel pad) (very low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs no treatment

Perineal oedema within 24 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack or cold gel pad) changes perineal oedema within 24 hours of giving birth compared with no treatment (very low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs no treatment

Perineal bruising within 24 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack or cold gel pad) changes perineal bruising within 24 hours of giving birth compared with no treatment (very low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs no treatment

Perineal bruising 24 ‐ 48 hours after giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

It is very uncertain whether cooling treatment (ice pack or cold gel pad) changes perineal bruising 24 ‐ 48 hours after giving birth compared with no treatment (very low certainty).

1 finding from 1 review

Any supplement containing iodine vs same supplement without iodine or no treatment/placebo (maternal outcomes)

Low birthweight · women during the preconception, pregnancy and postpartum period

Any supplement containing iodine showed no clear difference in low birthweight compared with same supplement without iodine or no treatment/placebo (child… (low certainty).

1 finding from 1 review

Any supplement containing iodine vs same supplement without iodine or no treatment/placebo (maternal outcomes)

Neonatal hypothyroidism or elevated TSH · women during the preconception, pregnancy and postpartum period

It is very uncertain whether any supplement containing iodine changes neonatal hypothyroidism or elevated TSH compared with same supplement without iodine or no treatment/placebo (child… (very low certainty).

1 finding from 1 review

Any supplement containing iodine vs same supplement without iodine or no treatment/placebo (maternal outcomes)

Neonatal adverse effect: elevated TPO‐ab · women during the preconception, pregnancy and postpartum period

It is very uncertain whether any supplement containing iodine changes neonatal adverse effect: elevated TPO‐ab compared with same supplement without iodine or no treatment/placebo (child… (very low certainty).

1 finding from 1 review

Any supplement containing iodine vs same supplement without iodine or no treatment/placebo (maternal outcomes)

Perinatal mortality · women during the preconception, pregnancy and postpartum period

Any supplement containing iodine showed no clear difference in perinatal mortality compared with same supplement without iodine or no treatment/placebo (child… (low certainty).

1 finding from 1 review