Participants with a serious adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with ≥ 1 adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with ≥ 1 adverse event following a single dose, and after 3 to 5 days · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with a serious adverse event following a single dose, and after 3 to 5 days · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Overall survival (OS) · non‐small cell lung cancer in the elderly population
Non‐platinum single‐agent may leads to lower overall survival (OS) compared with non‐platinum combination treatment (low certainty).
1 finding from 1 review
1‐Year survival rate (OS1y) · non‐small cell lung cancer in the elderly population
Non‐platinum single‐agent may leads to lower 1‐Year survival rate (OS1y) compared with non‐platinum combination treatment (low certainty).
1 finding from 1 review
Progression‐free survival · non‐small cell lung cancer in the elderly population
Non‐platinum single‐agent may leads to lower progression‐free survival compared with non‐platinum combination treatment (low certainty).
1 finding from 1 review
Objective response rate · non‐small cell lung cancer in the elderly population
Non‐platinum single‐agent may leads to higher objective response rate (ORR) compared with non‐platinum combination treatment (low certainty).
1 finding from 1 review
Grade 3 and 4 hematological adverse events (AE) ‐ anemia · non‐small cell lung cancer in the elderly population
It is very uncertain whether non‐platinum single‐agent changes grade 3 and 4 hematological adverse events (AE) ‐ anemia compared with non‐platinum combination treatment (very low certainty).
1 finding from 1 review
Grade 3 to 4 neutropenia · non‐small cell lung cancer in the elderly population
Non‐platinum single‐agent may leads to higher grade 3 and 4 hematological adverse events (AE) ‐ neutropenia compared with non‐platinum combination treatment (low certainty).
1 finding from 1 review
Safety (AE, adverse drug reaction): thrombocytopenia Grades 3 or 4 according to National Cancer Institute · non‐small cell lung cancer in the elderly population
It is very uncertain whether non‐platinum single‐agent changes grade 3 and 4 hematological adverse events (AE) ‐ thrombocytopenia compared with non‐platinum combination treatment (very low certainty).
1 finding from 1 review
QoL · non‐small cell lung cancer in the elderly population
1 finding from 1 review
Observed number of pregnancies (all women) · women seeking emergency contraception
Single‐dose levonorgestrel showed no clear difference in observed number of pregnancies (all women) compared with split‐dose levonorgestrel (moderate certainty).
1 finding from 1 review
Side effects · women seeking emergency contraception
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Nausea · women seeking emergency contraception
Single‐dose levonorgestrel showed no clear difference in specific side effects ‐ nausea compared with split‐dose levonorgestrel (moderate certainty).
1 finding from 1 review
Vomiting · women seeking emergency contraception
Single‐dose levonorgestrel showed no clear difference in specific side effects ‐ vomiting compared with split‐dose levonorgestrel (moderate certainty).
1 finding from 1 review
Specific side effects ‐ spotting/bleeding after treatment · women seeking emergency contraception
Single‐dose levonorgestrel showed no clear difference in specific side effects ‐ spotting/bleeding after treatment compared with split‐dose levonorgestrel (moderate certainty).
1 finding from 1 review
Menses ‐ early · women seeking emergency contraception
Single‐dose levonorgestrel leads to lower menses ‐ early compared with split‐dose levonorgestrel (high certainty).
1 finding from 1 review
Menses ‐ delay · women seeking emergency contraception
Single‐dose levonorgestrel showed no clear difference in menses ‐ delay compared with split‐dose levonorgestrel (low certainty).
1 finding from 1 review
Abdominal surgical site infection · people undergoing laparotomy for penetrating abdominal trauma
It is very uncertain whether single dose of antibiotics changes abdominal surgical site infection compared with 24 hours of antibiotics (very low certainty).
1 finding from 1 review