Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

870 questions · 912 findings · 85 reviews · Airways

No studies found 65 · 7.1%GRADE not reported 34 · 3.7%Very low 115 · 12.6%Low 273 · 29.9%Moderate 330 · 36.2%High 95 · 10.4%

28 days on/off antibiotic regimen vs 28 days on/off placebo regimen

Pulmonary exacerbations: number of hospitalisations due to respiratory exacerbations · people with bronchiectasis

28 days on/off antibiotic regimen showed no clear difference in hospitalisation for pulmonary exacerbations compared with 28 days on/off placebo regimen (high certainty).

1 finding from 1 review