Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

262 questions · 309 findings · 35 reviews

No studies found 66 · 21.4%GRADE not reported 46 · 14.9%Very low 85 · 27.5%Low 60 · 19.4%Moderate 38 · 12.3%High 14 · 4.5%

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus TAC plus 5‐FU ‐ mild to moderate pain related to treatment ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus TAC plus 5‐FU ‐ purpura ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus silicone gel sheeting ‐ skin irritation ‐ hypertrophic scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Scar severity ‐ erbium laser versus TAC ‐ patient self‐assessment ‐ patients considering the scar much better ‐ hypertrophic scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ erbium laser versus TAC ‐ patient self‐assessment ‐… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ fractional carbon dioxide (CO2) laser versus TAC ‐ pain at injection site ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ fractional CO2 laser versus TAC ‐ telangectasia ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ fractional CO2 laser versus TAC ‐ skin atrophy ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ fractional CO2 laser versus TAC ‐ charring ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ fractional CO2 laser versus verapamil ‐ pain at injection site ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ fractional CO2 laser versus verapamil ‐ charring ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐… compared with other treatments (very low certainty).

1 finding from 1 review

Silver diamine fluoride (SDF, including SDF + fluoride varnish) vs Other standard-of-care caries treatments pooled (placebo, ART, or ART + fluoride varnish)

Oral health-related quality of life · Children with dental caries

SDF had no significant effect on oral health-related quality of life versus pooled standard-of-care caries treatments (SMD -0.06, 95% CI -0.20 to 0.08; ungraded).

1 finding from 1 review

Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments

Effectiveness of treatment · health problem or population
3 findings from 1 review