Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,092 questions · 3,199 findings · 339 reviews · Headline outcomes only

No studies found 714 · 22.3%GRADE not reported 181 · 5.7%Very low 695 · 21.7%Low 908 · 28.4%Moderate 568 · 17.8%High 133 · 4.2%

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs oral antibiotics

Surgical site infection · Patients undergoing elective colorectal surgery

It is very uncertain whether summary of findings table ‐ Combined mechanical and oral antibiotic… changes surgical site infections compared with oral antibiotics alone (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs oral antibiotics

Anastomotic leakage · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in anastomotic leakage compared with oral antibiotics alone (low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs oral antibiotics

All‐cause mortality · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in mortality compared with oral antibiotics alone (low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs oral antibiotics

Postoperative ileus · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in incidence of postoperative ileus compared with oral antibiotics alone (low certainty).

1 finding from 1 review

Oral midazolam vs chloral hydrate

Level of sedation on a sedation assessment scale · children requiring sedation before procedures that require motion control, including echocardiography, lumbar puncture, micturating…
1 finding from 1 review

Oral midazolam vs chloral hydrate

Incomplete procedure · children requiring sedation before procedures that require motion control, including echocardiography, lumbar puncture, micturating…

Oral midazolam probably leads to higher incomplete procedures compared with chloral hydrate (moderate certainty).

1 finding from 1 review

Oral midazolam vs chloral hydrate

Anterograde amnesia (defined by number of participants who recalled the procedure) · children requiring sedation before procedures that require motion control, including echocardiography, lumbar puncture, micturating…

The review found no eligible studies for this question.

1 finding from 1 review

Oral midazolam vs chloral hydrate

Disinhibition or excitation · children requiring sedation before procedures that require motion control, including echocardiography, lumbar puncture, micturating…

The review found no eligible studies for this question.

1 finding from 1 review

Oral midazolam vs chloral hydrate

Patient discomfort · children requiring sedation before procedures that require motion control, including echocardiography, lumbar puncture, micturating…

The review found no eligible studies for this question.

1 finding from 1 review