Findings

What do systematic reviews say?

150 questions · 154 findings · 22 reviews · Eyes and Vision

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No studies found 6 · 3.9%GRADE not reported 3 · 1.9%Very low 44 · 28.6%Low 50 · 32.5%Moderate 48 · 31.2%High 3 · 1.9%

Intervention not reported

Multifocal spectacle lenses · children with progressive myopia (21 studies, 4169 participants in the analysis) Interventions: optical and pharmacological Comparator:…

1 finding from 1 review

Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 404 participants
Low

Intervention not reported

Undercorrected single vision spectacles · children with progressive myopia (21 studies, 4169 participants in the analysis) Interventions: optical and pharmacological Comparator:…

1 finding from 1 review

Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 122 participants
Low

Intervention not reported

Pirenzepine · children with progressive myopia (38 studies, 6525 participants in analyses) Interventions: optical and pharmacological Comparator:…

1 finding from 1 review

Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 210 participants
Very low

Intervention not reported

Multifocal soft contact lenses · children with progressive myopia (38 studies, 6525 participants in analyses) Interventions: optical and pharmacological Comparator:…

1 finding from 1 review

Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 712 participants
Very low

Intervention not reported

Rigid gas‐permeable contact lenses · children with progressive myopia (38 studies, 6525 participants in analyses) Interventions: optical and pharmacological Comparator:…

1 finding from 1 review

Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 178 participants
Very low

Intervention not reported

Peripheral plus spectacle lenses · children with progressive myopia (38 studies, 6525 participants in analyses) Interventions: optical and pharmacological Comparator:…

1 finding from 1 review

Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 480 participants
Very low

Intervention not reported

Multifocal spectacle lenses · children with progressive myopia (38 studies, 6525 participants in analyses) Interventions: optical and pharmacological Comparator:…

1 finding from 1 review

Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 729 participants
Low

Mitomycin C dacryocystorhinostomy vs dacryocystorhinostomy alone

Functional success, defined as the relief of epiphora · nasolacrimal duct obstruction

Mitomycin C dacryocystorhinostomy showed no clear difference in functional success, defined as the relief of epiphora compared with dacryocystorhinostomy alone (low certainty).

2 findings from 1 review

Antimetabolites as an adjunct to dacryocystorhinostomy for nasolacrimal duct obstruction 2020 · Cochrane Headline outcomes only
RR 1.12 [0.98, 1.29]
7 studies · 356 participants
Low
Antimetabolites as an adjunct to dacryocystorhinostomy for nasolacrimal duct obstruction 2020 · Cochrane Headline outcomes only
RR 1.15 [1.07, 1.25]
14 studies · 909 participants
Moderate

Mitomycin C dacryocystorhinostomy vs dacryocystorhinostomy alone

Anatomic success, defined as patency to lacrimal irrigation · nasolacrimal duct obstruction

Mitomycin C dacryocystorhinostomy showed no clear difference in anatomic success, defined as patency to lacrimal irrigation compared with dacryocystorhinostomy alone (low certainty).

2 findings from 1 review

Antimetabolites as an adjunct to dacryocystorhinostomy for nasolacrimal duct obstruction 2020 · Cochrane Headline outcomes only
RR 1.02 [0.95, 1.11]
4 studies · 306 participants
Low
Antimetabolites as an adjunct to dacryocystorhinostomy for nasolacrimal duct obstruction 2020 · Cochrane Headline outcomes only
RR 1.09 [1.04, 1.15]
12 studies · 831 participants
Moderate

Mitomycin C dacryocystorhinostomy vs dacryocystorhinostomy alone

Ostium size on nasal endoscopy · nasolacrimal duct obstruction

Mitomycin C dacryocystorhinostomy showed no clear difference in ostium size on nasal endoscopy compared with dacryocystorhinostomy alone (low certainty).

2 findings from 1 review

Antimetabolites as an adjunct to dacryocystorhinostomy for nasolacrimal duct obstruction 2020 · Cochrane Headline outcomes only
mean difference 3.7
2 studies · 65 participants
Low
Antimetabolites as an adjunct to dacryocystorhinostomy for nasolacrimal duct obstruction 2020 · Cochrane Headline outcomes only
MD 1.4
2 studies · 100 participants
Low