Findings

What do systematic reviews say?

185 questions · 187 findings · 25 reviews · Hypertension

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No studies found 20 · 10.7%GRADE not reported 8 · 4.3%Very low 27 · 14.4%Low 43 · 23%Moderate 27 · 14.4%High 62 · 33.2%

Intervention not reported

Diastolic BP ‐ Aliskiren 600 mg vs placebo · primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of renin inhibitors for primary hypertension 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 393 participants
Low

Intervention not reported

Diarrhoea ‐ Aliskiren 600 mg vs placebo · primary hypertension

The intervention may leads to higher diarrhoea ‐ Aliskiren 600 mg vs placebo (low certainty).

1 finding from 1 review

Blood pressure lowering efficacy of renin inhibitors for primary hypertension 2017 · Cochrane Headline outcomes only
RR 7 [2.48, 19.72]
2 studies · 592 participants
Low

Intervention not reported

End of treatment SBP (over 12 weeks) · patients with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 50 participants
Moderate

Intervention not reported

End of treatment DBP (over 12 weeks) · patients with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 50 participants
Moderate

Intervention not reported

Withdrawals due to adverse effects · patients with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
GRADE not reported

Intervention not reported

Systolic blood pressure · People with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of beta‐1 selective beta blockers for primary hypertension 2016 · Cochrane Headline outcomes only
no estimate extracted
47 studies · 5246 participants
Low

Intervention not reported

Diastolic blood pressure · People with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of beta‐1 selective beta blockers for primary hypertension 2016 · Cochrane Headline outcomes only
no estimate extracted
48 studies · 5316 participants
Low

Intervention not reported

Heart rate · People with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of beta‐1 selective beta blockers for primary hypertension 2016 · Cochrane Headline outcomes only
no estimate extracted
33 studies · 3407 participants
Low

Intervention not reported

Pulse pressure · People with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of beta‐1 selective beta blockers for primary hypertension 2016 · Cochrane Headline outcomes only
no estimate extracted
47 studies · 5246 participants
Very low

Intervention not reported

WDAE · People with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of beta‐1 selective beta blockers for primary hypertension 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 2618 participants
Low

Intervention not reported

Decrease in SBP mmHg mean duration 8.8 weeks · People with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of loop diuretics for primary hypertension 2015 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 460 participants
Low

Intervention not reported

Decrease in DBP mmHg mean duration 8.8 weeks · People with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of loop diuretics for primary hypertension 2015 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 460 participants
Low

Intervention not reported

Systolic blood pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension 2015 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1007 participants
Low

Intervention not reported

Diastolic blood pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension 2015 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1007 participants
Low

Intervention not reported

Heart rate · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension 2015 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 977 participants
Low

Intervention not reported

Pulse pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension 2015 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1007 participants
Very low

Intervention not reported

WDAE · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension 2015 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1412 participants
Moderate

Intervention not reported

LDL‐cholesterol atorvastatin 10 mg/d · individuals with normal or abnormal lipid profiles

1 finding from 1 review

Atorvastatin for lowering lipids 2015 · Cochrane Headline outcomes only
no estimate extracted
188 studies · 21941 participants
High

Intervention not reported

LDL‐cholesterol atorvastatin 20 mg/d · individuals with normal or abnormal lipid profiles

1 finding from 1 review

Atorvastatin for lowering lipids 2015 · Cochrane Headline outcomes only
no estimate extracted
80 studies · 9310 participants
High

Intervention not reported

LDL‐cholesterol atorvastatin 40 mg/d · individuals with normal or abnormal lipid profiles

1 finding from 1 review

Atorvastatin for lowering lipids 2015 · Cochrane Headline outcomes only
no estimate extracted
37 studies · 3296 participants
High