Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

179 questions · 205 findings · 42 reviews

No studies found 23 · 11.2%GRADE not reported 64 · 31.2%Very low 31 · 15.1%Low 51 · 24.9%Moderate 33 · 16.1%High 3 · 1.5%

CBT vs alternative treatment

Disability caused by pain at follow-up · People aged 12 years and over with painful TMD lasting 3 months or longer

Cognitive behavioural therapy (CBT) showed no clear difference in disability caused by pain at treatment completion compared with alternative (active) treatment (e.g. oral splint, medication,… (low certainty).

2 findings from 1 review

CBT vs inactive control (usual care care, attention control, waitlist)

Reduction in pain intensity · People aged 12 years and over with painful TMD lasting 3 months or longer

Cognitive behavioural therapy (CBT) may leads to lower pain intensity at follow-up (12 months) compared with usual care, waiting list or no treatment (control) (low certainty).

2 findings from 1 review

Hypnosis vs relaxation

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer

Hypnosis showed no clear difference in pain intensity compared with relaxation; GRADE not reported.

1 finding from 1 review
  • Psychological therapies for temporomandibular disorders (TMDs) 2022 · Cochrane All outcomes
    Treatment completion
    Not pooled (clinical heterogeneity). Abrahamsen 2011: MD -1.00 (95% CI -2.27 to 0.27), n=38 (hypnosis 19, relaxation 19); Stam 1984: MD not reported, n=27 (hypnosis 12, relaxation 15).
    2 studies · 65 participants
    GRADE not reported

Habit reversal vs waiting list control

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer

Habit reversal treatment led to lower pain intensity compared with waiting-list control; GRADE not reported.

1 finding from 1 review

Education vs usual care

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review

CBT plus hypnosis (combined package) vs usual care

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer

CBT plus hypnosis (combined package) led to lower pain intensity compared with usual care; GRADE not reported.

1 finding from 1 review

CBT vs inactive control (usual care care, attention control, waitlist)

Disability caused by pain at follow-up · People aged 12 years and over with painful TMD lasting 3 months or longer

Cognitive behavioural therapy (CBT) showed no clear difference in pain disability at treatment completion compared with usual care, waiting list or no treatment (control) (low certainty).

2 findings from 1 review

CBT vs inactive control (usual care care, attention control, waitlist)

Mental distress · People aged 12 years and over with painful TMD lasting 3 months or longer

Cognitive behavioural therapy (CBT) showed no clear difference in psychological distress at follow-up compared with usual care, waiting list or no treatment (control) (low certainty).

2 findings from 1 review

CBT vs alternative treatment

Adverse events · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review
  • SoF: 3 studies reported minor adverse events in the control group; 1 study reported minor adverse events in psychological therapy group; 1 study reported that there were no adverse events. Results: NCT00066937 minor…
    5 studies
    Very low

Removal of short‐term indwelling urethral catheters in adults after shorter vs longer durations

Number of participants requiring recatheterisation · adults with short‐term indwelling urethral catheters that need to be removed

Removal of short‐term indwelling urethral catheters in adults after… may leads to higher number of participants requiring recatheterisation compared with longer durations (low certainty).

1 finding from 1 review

Removal of short‐term indwelling urethral catheters in adults after shorter vs longer durations

Symptomatic catheter associated urinary tract infection · adults with short‐term indwelling urethral catheters that need to be removed

Removal of short‐term indwelling urethral catheters in adults after… probably leads to lower symptomatic catheter associated urinary tract infection (CAUTI) Â compared with longer durations (moderate certainty).

1 finding from 1 review

Removal of short‐term indwelling urethral catheters in adults after shorter vs longer durations

Dysuria · adults with short‐term indwelling urethral catheters that need to be removed

Removal of short‐term indwelling urethral catheters in adults after… may leads to lower dysuria compared with longer durations (low certainty).

1 finding from 1 review

Self‐monitoring or self‐management of oral anticoagulation vs usual care

Thromboembolic events · Patients on long‐term anticoagulant therapy (treatment duration longer than two months) irrespective of the indication for treatment

Self‐monitoring or self‐management of oral anticoagulation probably leads to lower thromboembolic events compared with standard care (moderate certainty).

1 finding from 1 review

self‐management of oral anticoagulation vs usual care

All‐cause mortality · Patients on long‐term anticoagulant therapy (treatment duration longer than two months) irrespective of the indication for treatment

self‐management of oral anticoagulation probably leads to lower all‐cause mortality compared with standard care (moderate certainty).

1 finding from 1 review

self‐management of oral anticoagulation vs usual care

Major bleeding · Patients on long‐term anticoagulant therapy (treatment duration longer than two months) irrespective of the indication for treatment

self‐management of oral anticoagulation showed no clear difference in major haemorrhage compared with standard care (low certainty).

1 finding from 1 review

self‐management of oral anticoagulation vs usual care

Minor haemorrhage · Patients on long‐term anticoagulant therapy (treatment duration longer than two months) irrespective of the indication for treatment

self‐management of oral anticoagulation showed no clear difference in minor haemorrhage compared with standard care (low certainty).

1 finding from 1 review