Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

556 questions · 586 findings · 44 reviews · Common Mental Disorders

No studies found 149 · 25.4%GRADE not reported 19 · 3.2%Very low 180 · 30.7%Low 160 · 27.3%Moderate 66 · 11.3%High 12 · 2%

Comparison 2.2: DBT group‐based skills training vs TAU or another comparator

Repetition of attempted suicide at post‐intervention · self‐harm in adults

Comparison 2.2: DBT group‐based skills training showed no clear difference in repetition of attempted suicide at post‐intervention compared with TAU or another comparator (moderate certainty).

1 finding from 1 review

New‐generation antidepressants vs placebo

Repetition of SH at post‐intervention · self‐harm in adults

It is very uncertain whether newer generation antidepressants (NGAs) changes repetition of SH by post‐intervention (NGA class)№ of participants:… compared with placebo (very low certainty).

3 findings from 1 review

Mood stabilisers vs placebo

Repetition of SH at post‐intervention · self‐harm in adults

It is very uncertain whether mood stabilisers, including antiepileptics and lithium changes repetition of SH by post‐intervention№ of participants: 167(1 RCT) compared with placebo (very low certainty).

1 finding from 1 review

Mindfulness vs no treatment or waiting list

Mental health and well‐being: stress or stress perceptionMeasured by: investigators measured stress or stress perception using different instruments; lower scores mean lower stress or stress perception Timing of outcome assessment: post‐intervention
1 finding from 1 review

Case management vs treatment

Repetition of SH at post‐intervention · adults who engage in SH

Comparison 3: Case management showed no clear difference in repetition of SH at post‐intervention compared with treatment (moderate certainty).

1 finding from 1 review

Case management vs treatment

Multiple readmissions for SH at post‐intervention · adults who engage in SH

Comparison 3: Case management probably leads to higher multiple readmissions for SH at post‐intervention compared with treatment (moderate certainty).

1 finding from 1 review

Discontinuation with high‐intensity psychological interventions vs continuation

Risk of relapse (as defined by study authors) (HR) · participants with long‐term antidepressants for depressive disorders

Discontinuation with high‐intensity psychological interventions showed no clear difference in risk of relapse (as defined by study authors) (HR) compared with continuation (low certainty).

1 finding from 1 review