Findings

What do systematic reviews say?

340 questions · 343 findings · 27 reviews · Musculoskeletal

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No studies found 66 · 19.2%GRADE not reported 25 · 7.3%Very low 64 · 18.7%Low 103 · 30%Moderate 54 · 15.7%High 31 · 9%

Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone

Withdrawals due to any reason · systemic lupus erythematosus

It is very uncertain whether summary of findings table ‐ Exercise plus usual pharmacological care changes withdrawals due to any reason compared with usual pharmacological care alone (very low certainty).

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
RR 0.92 [0.53, 1.6]
6 studies · 235 participants
Very low

Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care

Fatigue · systemic lupus erythematosus

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 119 participants
Low

Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care

Physical function · systemic lupus erythematosus

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 182 participants
Low

Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care

Disease activity · systemic lupus erythematosus

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 184 participants
Moderate

Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care

Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · systemic lupus erythematosus

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 121 participants
Low

Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care

Withdrawals due to any reason · systemic lupus erythematosus

It is very uncertain whether summary of findings table ‐ Exercise plus usual pharmacological care changes withdrawals due to any reason compared with another intervention (education, joint aids, or relaxation) plus… (very low certainty).

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
RR 0.89 [0.13, 5.94]
7 studies · 317 participants
Very low

Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo + standard care

Functional capacity · systemic lupus erythematosus

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Low

Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care

Serious adverse events ‐ not reported · systemic lupus erythematosus

The review found no eligible studies for this question.

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care

Quality of life ‐ not reported · systemic lupus erythematosus

The review found no eligible studies for this question.

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo + standard care

Pain (SF‐36 Bodily Pain domain, score 0‐100, lower scores indicate less pain) · systemic lupus erythematosus

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Low

Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo + standard care

Disease activity ‐ not measured · systemic lupus erythematosus

The review found no eligible studies for this question.

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo + standard care

Quality of life ‐ not measured · systemic lupus erythematosus

The review found no eligible studies for this question.

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo + standard care

Serious adverse events ‐ not reported · systemic lupus erythematosus

The review found no eligible studies for this question.

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo + standard care

Withdrawals due to any reason · systemic lupus erythematosus

It is very uncertain whether summary of findings table ‐ Exercise plus usual pharmacological care changes withdrawals due to any reason compared with placebo plus usual pharmacological care (very low certainty).

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
RR 2.73 [0.34, 22.16]
1 study · 21 participants
Very low

Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone

Fatigue · systemic lupus erythematosus

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 104 participants
Low

Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone

Physical function · systemic lupus erythematosus

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 96 participants
Low

Combination of manual therapy and exercise following joint distension vs sham ultrasound following joint distension

Participant‐reported pain relief of 30% or greater · patients with adhesive capsulitis (frozen shoulder)

The review found no eligible studies for this question.

1 finding from 1 review

Manual therapy and exercise for adhesive capsulitis (frozen shoulder) 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Combination of manual therapy and exercise following joint distension vs sham ultrasound following joint distension

Overall pain (change from baseline) · patients with adhesive capsulitis (frozen shoulder)

1 finding from 1 review

Manual therapy and exercise for adhesive capsulitis (frozen shoulder) 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 148 participants
High

Combination of manual therapy and exercise following joint distension vs sham ultrasound following joint distension

Function (change from baseline) Shoulder Pain and Disability Questionnaire (SPADI, 0‐100) (lower scores = better function)f · patients with adhesive capsulitis (frozen shoulder)

1 finding from 1 review

Manual therapy and exercise for adhesive capsulitis (frozen shoulder) 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 148 participants
High

Combination of manual therapy and exercise following joint distension vs sham ultrasound following joint distension

Active shoulder abduction · patients with adhesive capsulitis (frozen shoulder)

1 finding from 1 review

Manual therapy and exercise for adhesive capsulitis (frozen shoulder) 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 148 participants
High