Individual tailored showed no clear difference in death or cerebral palsy at 1 to 3 years compared with continuous tapered dexamethasone regimen (moderate certainty).

1 finding from 1 review

Systemic corticosteroid regimens for prevention of bronchopulmonary dysplasia in preterm infants 2023 · Cochrane Headline outcomes only
RR 7.24 [0.95, 55.26]
1 study · 59 participants
Moderate

Individual tailored vs continuous tapered dexamethasone regimen

Death or abnormal neurodevelopmental outcome (various definitions) · preterm infants at risk for bronchopulmonary dysplasia

Individual tailored showed no clear difference in death or abnormal neurodevelopmental outcome (various definitions) compared with continuous tapered dexamethasone regimen (low certainty).

1 finding from 1 review

Systemic corticosteroid regimens for prevention of bronchopulmonary dysplasia in preterm infants 2023 · Cochrane Headline outcomes only
RR 1.44 [0.99, 2.07]
3 studies · 168 participants
Low

Individual tailored vs continuous tapered dexamethasone regimen

Death or bronchopulmonary dysplasia at 36 weeks PMA · preterm infants at risk for bronchopulmonary dysplasia

Individual tailored showed no clear difference in death or bronchopulmonary dysplasia at 36 weeks PMA compared with continuous tapered dexamethasone regimen (low certainty).

1 finding from 1 review

Systemic corticosteroid regimens for prevention of bronchopulmonary dysplasia in preterm infants 2023 · Cochrane Headline outcomes only
RR 1.06 [0.88, 1.29]
3 studies · 168 participants
Low

Dual antiplatelet therapy vs one antiplatelet agent

Stroke · people with antiphospholipid syndrome, with previous stroke

It is very uncertain whether dual antiplatelet agent changes stroke compared with single antiplatelet agent (very low certainty).

1 finding from 1 review

Antiplatelet and anticoagulant agents for secondary prevention of stroke and other thromboembolic events in people… 2020 · Cochrane Headline outcomes only
RR 0.14 [0.01, 2.6]
1 study · 40 participants
Very low

Dual mini-screw implant vs Single mini-screw implant

Economic factors · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

The review found no eligible studies for this question.

1 finding from 1 review

Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods 2014 · Cochrane All outcomes
Economic factors were not reported in any of the studies comparing two types of surgical anchorage
0 studies
No studies found

Dual mini-screw implant vs Single mini-screw implant

Number of visits · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

The review found no eligible studies for this question.

1 finding from 1 review

Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods 2014 · Cochrane All outcomes
No studies reported on the number of visits for the comparison of two types of surgical anchorage
0 studies
No studies found

Dual mini-screw implant vs Single mini-screw implant

Success of the anchorage device · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Dual mini-screw implant showed no clear difference in success of the anchorage device compared with single mini-screw implant; GRADE not reported.

1 finding from 1 review

Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods 2014 · Cochrane All outcomes
RR 1.01 [0.84, 1.22]
1 study · 25 participants
GRADE not reported

Dual mini-screw implant vs Single mini-screw implant

Duration of space closure · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Dual mini-screw implant showed no clear difference in duration of space closure compared with single mini-screw implant; GRADE not reported.

1 finding from 1 review

Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods 2014 · Cochrane All outcomes
MD -2.19 [-6.35, 1.97]
1 study · 25 participants
GRADE not reported

Dual mini-screw implant vs Single mini-screw implant

Mesiodistal movement of the upper first permanent molar · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Dual mini-screw implant led to higher mesiodistal movement of the upper first permanent molar compared with single mini-screw implant; GRADE not reported.

1 finding from 1 review

Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods 2014 · Cochrane All outcomes
MD 1.62 [0.98, 2.26]
1 study · 25 participants
GRADE not reported

Dual mini-screw implant vs Single mini-screw implant

Acceptability · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

The review found no eligible studies for this question.

1 finding from 1 review

Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods 2014 · Cochrane All outcomes
Acceptability was not reported in any of the studies comparing two types of surgical anchorage
0 studies
No studies found

Dual mini-screw implant vs Single mini-screw implant

Adverse effects · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

The review found no eligible studies for this question.

1 finding from 1 review

Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods 2014 · Cochrane All outcomes
Adverse effects were not reported in any of the studies comparing two types of surgical anchorage
0 studies
No studies found

Dual antiplatelet therapy vs one antiplatelet agent

Cognitive function · people with cerebral small vessel disease and no dementia

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 3020 participants
Low

Dual antiplatelet therapy vs one antiplatelet agent

Incidence of dementia · people with cerebral small vessel disease and no dementia

The review found no eligible studies for this question.

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Dual antiplatelet therapy vs one antiplatelet agent

Major bleeding (intracranial and extracranial) · people with cerebral small vessel disease and no dementia

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 3020 participants
Low

Dual antiplatelet therapy vs one antiplatelet agent

Functional ability · people with cerebral small vessel disease and no dementia

The review found no eligible studies for this question.

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Dual antiplatelet therapy vs one antiplatelet agent

Stroke or transient ischaemic attack · people with cerebral small vessel disease and no dementia

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 3020 participants
Low

Dual antiplatelet therapy vs one antiplatelet agent

Any adverse events (excluding major bleeding) · people with cerebral small vessel disease and no dementia

The review found no eligible studies for this question.

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found