Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

157 questions · 158 findings · 44 reviews · Headline outcomes only

No studies found 25 · 15.8%GRADE not reported 7 · 4.4%Very low 40 · 25.3%Low 50 · 31.6%Moderate 33 · 20.9%High 3 · 1.9%

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Mean refractive error expressed as mean spherical equivalent post‐treatment. ‐ 12 months · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism
1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Adverse effects: corneal haze · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism

It is very uncertain whether laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… changes corneal haze, any time point compared with LASIK with a femtosecond laser (very low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Dry eye, any time point · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… may leads to higher dry eye, any time point compared with LASIK with a femtosecond laser (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Diffuse lamellar keratitis, any time point · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… may leads to lower diffuse lamellar keratitis, any time point compared with LASIK with a femtosecond laser (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Epithelial ingrowth, any time point · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism

It is very uncertain whether laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… changes epithelial ingrowth, any time point compared with LASIK with a femtosecond laser (very low certainty).

1 finding from 1 review

Intervention not reported

False positives (participants incorrectly classified as having pneumonic plague) · s where plague has been known to occur and populations where an outbreak is in progress Patient or population: adults and children with…
1 finding from 1 review

Intervention not reported

Test result · s where plague has been known to occur and populations where an outbreak is in progress Patient or population: adults and children with…
1 finding from 1 review

Intervention not reported

True positives (participants correctly classified as having pneumonic plague) · s where plague has been known to occur and populations where an outbreak is in progress Patient or population: adults and children with…
1 finding from 1 review

Intervention not reported

False negatives (participants incorrectly classified as not having pneumonic plague) · s where plague has been known to occur and populations where an outbreak is in progress Patient or population: adults and children with…
1 finding from 1 review

Intervention not reported

True negatives (participants correctly classified as not having pneumonic plague) · s where plague has been known to occur and populations where an outbreak is in progress Patient or population: adults and children with…
1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Re‐bleeding Bleeding after initial success in the intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes re‐bleeding Bleeding after initial success in the intervention compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Control of bleeding Success in control the active variceal bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes control of bleeding Success in control the active variceal bleeding compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Total mortality Total deaths and the end of · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes total mortality Total deaths and the end of compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

day ‐ mortality Mortality due to bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes day ‐ mortality Mortality due to bleeding compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Failure of intervention Continuous bleeding after intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes failure of intervention Continuous bleeding after intervention compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Complications (fever) Presence of fever · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes complications (fever) Presence of fever compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review