Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,733 questions · 1,794 findings · 326 reviews · Headline outcomes only

No studies found 243 · 13.5%GRADE not reported 96 · 5.4%Very low 597 · 33.3%Low 506 · 28.2%Moderate 303 · 16.9%High 49 · 2.7%

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related infectious complications ‐ Catheter colonization · critically ill patients who were expected to require support with renal replacement therapy

Femoral showed no clear difference in catheter‐related infectious complications ‐ Catheter colonization compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related blood stream infection · critically ill patients who were expected to require support with renal replacement therapy

Femoral showed no clear difference in catheter‐related infectious complications ‐ Catheter related… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related infectious complication ‐ Subgroup Analysis for the effect of BMI on catheter colonization ‐ Highest BMI tercile (>28.4) · critically ill patients who were expected to require support with renal replacement therapy

Femoral probably leads to higher catheter‐related infectious complication ‐ Subgroup Analysis for the… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related thrombotic complications ‐ Symptomatic deep venous thrombosis · critically ill patients who were expected to require support with renal replacement therapy

Femoral showed no clear difference in catheter‐related thrombotic complications ‐ Symptomatic deep venous… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related thrombosis at any time during catheter stay · critically ill patients who were expected to require support with renal replacement therapy

Femoral showed no clear difference in catheter‐related thrombotic complications ‐ Catheter related… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Immediate mechanical complications ‐ Total mechanical complications · critically ill patients who were expected to require support with renal replacement therapy

Femoral probably leads to lower immediate mechanical complications ‐ Total mechanical complications compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Immediate mechanical complications ‐ Major mechanical complications · critically ill patients who were expected to require support with renal replacement therapy

Femoral showed no clear difference in immediate mechanical complications ‐ Major mechanical complications compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs subclavian insertion: short‐term catheterization

Catheter‐related infectious complications ‐ Catheter colonization · critically ill patients

Femoral leads to higher catheter‐related infectious complications ‐ Catheter colonization compared with subclavian insertion: short‐term catheterization (high certainty).

1 finding from 1 review

Femoral vs subclavian insertion: short‐term catheterization

Catheter‐related blood stream infection · critically ill patients

Femoral showed no clear difference in catheter‐related infectious complications ‐ Catheter‐related… compared with subclavian insertion: short‐term catheterization (high certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Infant HIV Transmission or Death at 6 Months · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

Kesho Bora: AZT/3TC/LPV‐r showed no clear difference in infant HIV Transmission or Death at 6 Months compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (low certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Mother to Child Transmission at Birth · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

Kesho Bora continued: AZT/3TC/LPV‐r showed no clear difference in mother to Child Transmission at Birth compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (low certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Mother to Child Transmission at 6 Weeks · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

Kesho Bora continued: AZT/3TC/LPV‐r showed no clear difference in mother to Child Transmission at 6 Weeks compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (low certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Mother to Child Transmission at 6 Months · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

Kesho Bora continued: AZT/3TC/LPV‐r may leads to lower mother to Child Transmission at 6 Months compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (low certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Mother to Child Transmission at 12 Months · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

It is very uncertain whether kesho Bora continued: AZT/3TC/LPV‐r changes mother to Child Transmission at 12 Months compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (very low certainty).

1 finding from 1 review