Findings
What do systematic reviews say? 4,771 questions · 10,185 findings · 893 reviews
No studies found 2,109 · 20.7% GRADE not reported 1,125 · 11% Very low 2,279 · 22.4% Low 2,514 · 24.7% Moderate 1,709 · 16.8% High 449 · 4.4%
Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.
Radiographic joint changes · Patients with osteoarthritis of the knee or hip
1 finding from 1 review
Adverse events · Patients with osteoarthritis of the knee or hip
Summary of findings table ‐ Adjunctive therapies in addition to… showed no clear difference in adverse events compared with placebo adjunctive therapies (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · Patients with osteoarthritis of the knee or hip
1 finding from 1 review
All‐cause mortality
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cardiovascular mortality
1 finding from 1 review
Non‐fatal MI
1 finding from 1 review
Non‐fatal stroke
1 finding from 1 review
End‐stage renal disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality
It is very uncertain whether summary of findings of metformin monotherapy for adults with type 2… changes all‐cause mortality compared with thiazolidinediones (very low certainty).
1 finding from 1 review
SAEs
It is very uncertain whether summary of findings of metformin monotherapy for adults with type 2… changes serious adverse events (SAE) compared with thiazolidinediones (very low certainty).
1 finding from 1 review
Health‐related quality of life
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cardiovascular mortality
It is very uncertain whether summary of findings of metformin monotherapy for adults with type 2… changes cardiovascular mortality (CVM) compared with thiazolidinediones (very low certainty).
1 finding from 1 review
Non‐fatal MI
1 finding from 1 review
Serious adverse events
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Non‐fatal stroke
1 finding from 1 review
End‐stage renal disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality
1 finding from 1 review
SAEs
1 finding from 1 review
Health‐related quality of life
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
evidence gaps · evidencegaps.com
Not clinical guidance. Data from the Cochrane Library (Summary of Findings tables and full text), PubMed and Crossref, extracted by the Evidence Gaps pipeline. Related-question groupings and the gap map key are proposals pending human validation. A review that found no studies, or no review at all, is not proof that no research exists.