Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,018 questions · 3,100 findings · 369 reviews · Headline outcomes only

No studies found 774 · 25%GRADE not reported 108 · 3.5%Very low 727 · 23.5%Low 840 · 27.1%Moderate 474 · 15.3%High 177 · 5.7%

Antibiotics vs placebo

Clinical failure · acute rhinosinusitis in adults, whether clinically diagnosed or confirmed by imaging

Antibiotics leads to lower clinical failure compared with placebo (high certainty).

1 finding from 1 review

Single herb plus conventional intervention vs conventional intervention

Visual improvement at end of treatment, as defined by two or more Snellen lines · people with diabetic retinopathy

Single herb plus conventional intervention may leads to higher visual acuity (gain of ≥ 2 lines) (end of treatment) compared with conventional intervention (low certainty).

1 finding from 1 review

Single herb plus conventional intervention vs conventional intervention

Observations in retina: reduction in haemorrhages · people with diabetic retinopathy

It is very uncertain whether single herb plus conventional intervention changes observations in retina: reduction in haemorrhages compared with conventional intervention (very low certainty).

1 finding from 1 review