Findings

What do systematic reviews say?

1,733 questions · 1,794 findings · 326 reviews · Headline outcomes only

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No studies found 243 · 13.5%GRADE not reported 96 · 5.4%Very low 597 · 33.3%Low 506 · 28.2%Moderate 303 · 16.9%High 49 · 2.7%

Atypical vs atypical antipsychotics (only short term)

No improvement (clozapine vs olanzapine) · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
High

Atypical vs atypical antipsychotics (only short term)

Use of other antipsychotics · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Moderate

Atypical vs atypical antipsychotics (only short term)

Drug‐induced diabetes (clozapine vs olanzapine) · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Moderate

Atypical vs atypical antipsychotics (only short term)

Elevated prolactin (risperidone vs quetiapine) · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Moderate

Atypical vs atypical antipsychotics (only short term)

Weight gain · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 76 participants
High

Atypical vs atypical antipsychotics (only short term)

Leaving the study early because of weight gain (risperidone vs olanzapine) · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 19 participants
Low

Atypical (standard‐dose) vs atypical (low‐dose) antipsychotics (only short term)

No response · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 255 participants
High

Atypical (standard‐dose) vs atypical (low‐dose) antipsychotics (only short term)

Symptomatic hyperprolactinaemia · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 257 participants
High

Atypical (standard‐dose) vs atypical (low‐dose) antipsychotics (only short term)

Use of antiparkinsonian medications · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 257 participants
High

Atypical (standard‐dose) vs atypical (low‐dose) antipsychotics (only short term)

Weight gain · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 257 participants
High

Atypical antipsychotics vs placebo (only short term)

Weight gain (equal or greater then 7% of baseline) · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 106 participants
High

Atypical antipsychotics vs placebo (only short term)

High prolactin at any time during treatment · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 107 participants
High

Atypical antipsychotics vs placebo (only short term)

Change in corrected QT · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 107 participants
High

Atypical vs typical antipsychotics (only short term)

Worse or no improvement · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Low

Atypical vs typical antipsychotics (only short term)

Adverse effects ‐ anticholinergic effects · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Moderate

Atypical vs typical antipsychotics (only short term)

Drop in the absolute neutrophil count below 1500 per mm3 · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low

Atypical vs typical antipsychotics (only short term)

Adverse effects: Leaving the study early · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Moderate

Atypical vs atypical antipsychotics (only short term)

No improvement (risperidone vs olanzapine) · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 111 participants
Moderate

Femoral vs subclavian insertion: short‐term catheterization

Immediate mechanical complications ‐ Total mechanical complications · critically ill patients

Femoral showed no clear difference in immediate mechanical complications ‐ Total mechanical complications compared with subclavian insertion: short‐term catheterization (high certainty).

1 finding from 1 review

Central venous access sites for the prevention of venous thrombosis, stenosis and infection 2012 · Cochrane Headline outcomes only
RR 0.92 [0.56, 1.51]
1 study · 289 participants
High

Femoral vs subclavian insertion: short‐term catheterization

Immediate mechanical complications ‐ Major mechanical complications · critically ill patients

Femoral showed no clear difference in immediate mechanical complications ‐ Major mechanical complications compared with subclavian insertion: short‐term catheterization (high certainty).

1 finding from 1 review

Central venous access sites for the prevention of venous thrombosis, stenosis and infection 2012 · Cochrane Headline outcomes only
RR 0.5 [0.09, 2.67]
1 study · 289 participants
High