Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only

No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%

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Summary of Findings Table ‐ Electrocoagulation alone vs control (vehicle solution of allopurinol by mouth)

All‐cause mortality at last · people with liver metastases

It is very uncertain whether summary of Findings Table ‐ Electrocoagulation alone changes all‐cause mortality at last compared with control (vehicle solution of allopurinol by mouth) (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Electrocoagulation alone vs control (vehicle solution of allopurinol by mouth)

Post‐operative deaths · people with liver metastases

It is very uncertain whether summary of Findings Table ‐ Electrocoagulation alone changes post‐operative deaths compared with control (vehicle solution of allopurinol by mouth) (very low certainty).

1 finding from 1 review

Raloxifene vs placebo

Adverse events ‐ pelvic pain · women with endometriosis, following complete surgical excision of lesions

It is very uncertain whether raloxifene changes adverse events ‐ pelvic pain compared with placebo (very low certainty).

1 finding from 1 review

Raloxifene vs placebo

Adverse events ‐ ovarian cyst · women with endometriosis, following complete surgical excision of lesions

It is very uncertain whether raloxifene changes adverse events ‐ ovarian cyst compared with placebo (very low certainty).

1 finding from 1 review

Raloxifene vs placebo

Adverse events ‐ depression · women with endometriosis, following complete surgical excision of lesions

It is very uncertain whether raloxifene changes adverse events ‐ depression compared with placebo (very low certainty).

1 finding from 1 review

High‐dose chemotherapy followed by autologous haematopoietic cell transplantation vs conventional chemotherapy plus whole lung irradiation

Event‐free survival · children, adolescents, and young adults with primary metastatic Ewing sarcoma

High‐dose chemotherapy followed by autologous haematopoietic cell… showed no clear difference in event‐free survival (reported as number of participants with… compared with conventional chemotherapy plus whole lung irradiation (low certainty).

1 finding from 1 review

High‐dose chemotherapy followed by autologous haematopoietic cell transplantation vs conventional chemotherapy plus whole lung irradiation

Overall survival · children, adolescents, and young adults with primary metastatic Ewing sarcoma

The review found no eligible studies for this question.

1 finding from 1 review

High‐dose chemotherapy followed by autologous haematopoietic cell transplantation vs conventional chemotherapy plus whole lung irradiation

Quality‐adjusted survival · children, adolescents, and young adults with primary metastatic Ewing sarcoma

The review found no eligible studies for this question.

1 finding from 1 review

High‐dose chemotherapy followed by autologous haematopoietic cell transplantation vs conventional chemotherapy plus whole lung irradiation

Toxicity · children, adolescents, and young adults with primary metastatic Ewing sarcoma

The review found no eligible studies for this question.

1 finding from 1 review

High‐dose chemotherapy followed by autologous haematopoietic cell transplantation vs conventional chemotherapy plus whole lung irradiation

Progression‐free survival · children, adolescents, and young adults with primary metastatic Ewing sarcoma

The review found no eligible studies for this question.

1 finding from 1 review