Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,718 questions · 1,762 findings · 100 reviews · Headline outcomes only

No studies found 507 · 28.8%GRADE not reported 115 · 6.5%Very low 556 · 31.6%Low 444 · 25.2%Moderate 114 · 6.5%High 26 · 1.5%

Summary of findings table ‐ Remifentanil vs placebo

Pain ‐ remifentanil · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide

Remifentanil may leads to lower pain ‐ remifentanil compared with placebo (low certainty).

1 finding from 1 review

Systemic antispasticity drugs vs placebo

Indirect measure of spasticity Modified Ashworth Scale · people with spasticity following stroke

It is very uncertain whether systemic antispasticity drugs changes indirect measure of spasticity Modified Ashworth Scale compared with placebo (very low certainty).

1 finding from 1 review

Psychological therapies vs tricyclic antidepressants (TCAs)

Short‐term improvement Scale used (range; lower is better): Clinical Global Impression (1 to 7) Agoraphobic Cognitions Questionnaire (1 to 70) Panic Disorder Severity Scale (0 to 28) Brief Scale for Anxiety (0 to 60) · adults with panic disorder
1 finding from 1 review