Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,262 questions · 2,405 findings · 248 reviews · Headline outcomes only

No studies found 507 · 21.1%GRADE not reported 93 · 3.9%Very low 657 · 27.3%Low 708 · 29.4%Moderate 387 · 16.1%High 53 · 2.2%

BoNT‐A vs usual care or physiotherapy

Function · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Range of motion (passive ankle dorsiflexion) · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Satisfaction (not measured) · children with CP

The review found no eligible studies for this question.

2 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Spasticity (ankle plantarflexors) · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Adverse events · children with CP

The review found no eligible studies for this question.

3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Gait assessment ‐ not measured · children with CP

The review found no eligible studies for this question.

2 findings from 1 review

Corticosteroids vs placebo or usual care

Number of participants with adverse events ‐ superinfection (up to longest · children and adults with sepsis

Corticosteroids showed no clear difference in number of participants with adverse events ‐ superinfection (up to… compared with placebo or usual care (moderate certainty).

1 finding from 1 review