Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,288 questions · 3,354 findings · 516 reviews · Headline outcomes only

No studies found 720 · 21.5%GRADE not reported 164 · 4.9%Very low 950 · 28.3%Low 932 · 27.8%Moderate 434 · 12.9%High 154 · 4.6%

Pre‐emptive antifungal therapy vs empirical antifungal therapy

Proportion of antifungal agent use (other than prophylactic use) · people with cancer who have febrile neutropenia

It is very uncertain whether pre‐emptive antifungal therapy changes proportion of antifungal agent use (other than prophylactic use) compared with empirical antifungal therapy (very low certainty).

1 finding from 1 review

Pre‐emptive antifungal therapy vs empirical antifungal therapy

Duration of antifungal use (days) · people with cancer who have febrile neutropenia

It is very uncertain whether pre‐emptive antifungal therapy changes duration of antifungal use (days) compared with empirical antifungal therapy (very low certainty).

1 finding from 1 review

Pre‐emptive antifungal therapy vs empirical antifungal therapy

Invasive fungal infection detection · people with cancer who have febrile neutropenia

It is very uncertain whether pre‐emptive antifungal therapy changes invasive fungal infection detection compared with empirical antifungal therapy (very low certainty).

1 finding from 1 review