Question · asked by 1 review

Pre‐emptive antifungal therapy vs empirical antifungal therapy: Duration of antifungal use (days)

It is very uncertain whether pre‐emptive antifungal therapy changes duration of antifungal use (days) compared with empirical antifungal therapy (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Pre‐emptive antifungal therapy vs empirical antifungal therapy
Duration of antifungal use (days) · people with cancer who have febrile neutropenia
It is very uncertain whether pre‐emptive antifungal therapy changes duration of antifungal use (days) compared with empirical antifungal therapy (very low certainty).
Pre‐emptive antifungal therapy versus empirical antifungal therapy for febrile neutropenia in people with… (2022) · Cochrane Headline outcomes only
no estimate extracted3 studies · 764 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pre‐emptive antifungal therapy versus empirical antifungal therapy for febrile neutropenia in people with cancer
2022 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.