What do systematic reviews say?

1,438 questions · 1,463 findings · 125 reviews · Anaesthesia

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No studies found 197 · 13.5%GRADE not reported 203 · 13.9%Very low 307 · 21%Low 441 · 30.1%Moderate 245 · 16.7%High 70 · 4.8%

Music‐based therapeutic interventions vs usual care

Diastolic blood pressure · patients with preoperative anxiety

1 finding from 1 review

Music interventions for preoperative anxiety 2013 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 786 participants
Very low

Music‐based therapeutic interventions vs usual care

Vital signs ‐ respiratory rate · patients with preoperative anxiety

1 finding from 1 review

Music interventions for preoperative anxiety 2013 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 375 participants
Very low

Neuraxial vs general anaesthesia

Mortality－At any time · people who underwent a lower limb revascularisation

Neuraxial showed no clear difference in mortality－At any time compared with general anaesthesia (low certainty).

1 finding from 1 review

Neuraxial anaesthesia for lower‐limb revascularization 2013 · Cochrane Headline outcomes only
OR 0.89 [0.38, 2.07]
4 studies · 696 participants
Low

Neuraxial vs general anaesthesia

Myocardial infarction ‐ Spinal anaesthesia · people who underwent a lower limb revascularisation

Neuraxial showed no clear difference in myocardial infarction－Spinal anaesthesia compared with general anaesthesia (low certainty).

1 finding from 1 review

Neuraxial anaesthesia for lower‐limb revascularization 2013 · Cochrane Headline outcomes only
OR 1.89 [0.5, 7.21]
2 studies · 306 participants
Low

Neuraxial vs general anaesthesia

Myocardial infarction ‐ Epidural anaesthesia · people who underwent a lower limb revascularisation

Neuraxial showed no clear difference in myocardial infarction－Epidural anaesthesia compared with general anaesthesia (low certainty).

1 finding from 1 review

Neuraxial anaesthesia for lower‐limb revascularization 2013 · Cochrane Headline outcomes only
OR 0.98 [0.37, 2.58]
3 studies · 390 participants
Low

Neuraxial vs general anaesthesia

Amputation rate ‐ Spinal anaesthesia · people who underwent a lower limb revascularisation

Neuraxial showed no clear difference in amputation rate－Spinal anaesthesia compared with general anaesthesia (low certainty).

1 finding from 1 review

Neuraxial anaesthesia for lower‐limb revascularization 2013 · Cochrane Headline outcomes only
OR 1.04 [0.35, 3.06]
2 studies · 235 participants
Low

Neuraxial vs general anaesthesia

Amputation rate ‐ Epidural anaesthesia · people who underwent a lower limb revascularisation

Neuraxial showed no clear difference in amputation rate－Epidural anaesthesia compared with general anaesthesia (low certainty).

1 finding from 1 review

Neuraxial anaesthesia for lower‐limb revascularization 2013 · Cochrane Headline outcomes only
OR 0.66 [0.21, 2.07]
2 studies · 230 participants
Low

Neuraxial vs general anaesthesia

Pneumonia · people who underwent a lower limb revascularisation

It is very uncertain whether neuraxial changes pneumonia compared with general anaesthesia (very low certainty).

1 finding from 1 review

Neuraxial anaesthesia for lower‐limb revascularization 2013 · Cochrane Headline outcomes only
OR 0.37 [0.15, 0.89]
2 studies · 201 participants
Very low

Perioperative statins vs placebo or no treatment

All‐cause mortality · participants with improving outcomes during and after noncardiac vascular surgery.

Perioperative statins showed no clear difference in all‐cause mortality compared with placebo or no treatment (low certainty).

1 finding from 1 review

Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery 2013 · Cochrane Headline outcomes only
RR 0.73 [0.31, 1.75]
3 studies · 178 participants
Low

Perioperative statins vs placebo or no treatment

All cardiovascular death · participants with improving outcomes during and after noncardiac vascular surgery.

Perioperative statins showed no clear difference in death from cardiovascular causes compared with placebo or no treatment (low certainty).

1 finding from 1 review

Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery 2013 · Cochrane Headline outcomes only
RR 1.05 [0.07, 16.2]
3 studies · 178 participants
Low

Perioperative statins vs placebo or no treatment

Non‐fatal MI · participants with improving outcomes during and after noncardiac vascular surgery.

Perioperative statins showed no clear difference in myocardial infarction (non‐fatal) compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery 2013 · Cochrane Headline outcomes only
RR 0.47 [0.15, 1.52]
3 studies · 178 participants
Moderate

Perioperative statins vs placebo or no treatment

Stroke/TIA (non‐fatal) · participants with improving outcomes during and after noncardiac vascular surgery.

Perioperative statins showed no clear difference in stroke/TIA (non‐fatal) compared with placebo or no treatment (low certainty).

1 finding from 1 review

Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery 2013 · Cochrane Headline outcomes only
RR 0.24 [0.03, 2.25]
3 studies · 178 participants
Low

Perioperative statins vs placebo or no treatment

Participant‐reported outcomes－not measured · participants with improving outcomes during and after noncardiac vascular surgery.

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Perioperative statins vs placebo or no treatment

Adverse muscle effects · participants with improving outcomes during and after noncardiac vascular surgery.

1 finding from 1 review

Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery 2013 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 188 participants
GRADE not reported

PLMA vs tracheal tube

Failed placement/change of device · airway management during general anaesthesia in obese participants

1 finding from 1 review

Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in obese… 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 118 participants
Low

PLMA vs tracheal tube

Episodes of hypoxaemia in PACU < 92% oxygen saturation · airway management during general anaesthesia in obese participants

PLMA probably leads to lower episodes of hypoxaemia in PACU < 92% oxygen saturation compared with tracheal tube (moderate certainty).

1 finding from 1 review

Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in obese… 2013 · Cochrane Headline outcomes only
RR 0.27 [0.1, 0.72]
1 study · 70 participants
Moderate

PLMA vs tracheal tube

Oxygen Saturation Level · airway management during general anaesthesia in obese participants

1 finding from 1 review

Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in obese… 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 204 participants
Low

PLMA vs tracheal tube

Pulmonary aspiration of gastric contents · airway management during general anaesthesia in obese participants

1 finding from 1 review

Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in obese… 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 232 participants
GRADE not reported

PLMA vs tracheal tube

Serious respiratory complications and mortality－not reported · airway management during general anaesthesia in obese participants

The review found no eligible studies for this question.

1 finding from 1 review

Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in obese… 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PLMA vs tracheal tube

Laryngospasm/bronchoconstriction between induction and recovery · airway management during general anaesthesia in obese participants

It is very uncertain whether PLMA changes laryngospasm/bronchoconstriction between induction and recovery compared with tracheal tube (very low certainty).

1 finding from 1 review

Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in obese… 2013 · Cochrane Headline outcomes only
RR 0.5 [0.09, 2.84]
2 studies · 232 participants
Very low