Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,721 questions · 19,640 findings · 2,039 reviews · Headline outcomes only

No studies found 3,754 · 19.1%GRADE not reported 1,273 · 6.5%Very low 4,859 · 24.7%Low 5,568 · 28.4%Moderate 3,240 · 16.5%High 946 · 4.8%

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Intratympanic corticosteroids vs no treatment or versus placebo

Change in hearing threshold determined by PTA Range 0 dB to 140 dB Negative values represent lowering and positive values represent raising of the hearing threshold. A lower hearing threshold represents hearing improvement. Â · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in change in hearing threshold determined by PTA Range 0 dB to 140 dB… compared with no treatment or versus placebo (low certainty).

1 finding from 1 review

Intratympanic corticosteroids vs no treatment or versus placebo

Final hearing threshold determined by PTA (a lower value represents better hearing) · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in final hearing threshold determined by PTA (a lower value represents… compared with no treatment or versus placebo (low certainty).

1 finding from 1 review

Intratympanic corticosteroids vs systemic corticosteroids

Final hearing threshold determined by PTA (a lower value represents better hearing) · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in final hearing threshold determined by PTA (a lower value represents… compared with systemic corticosteroids (low certainty).

1 finding from 1 review

Intervention not reported

Symblepharon Presence of symblepharon · people with severe acute ocular burns

The intervention showed no clear difference in symblepharon Presence of symblepharon (low certainty).

1 finding from 1 review

Intervention not reported

Symblepharon Presence of symblepharon · people with moderate acute ocular burns

It is very uncertain whether the intervention changes symblepharon Presence of symblepharon (very low certainty).

1 finding from 1 review

Malaria rapid diagnostic test (mRDT) vs clinical diagnosis

Antimalarial prescribing to microscopy‐ or PCR‐negative people · people with suspected malaria

Malaria rapid diagnostic test (mRDT) probably leads to lower antimalarial prescribing to microscopy‐ or PCR‐negative people compared with clinical diagnosis (moderate certainty).

1 finding from 1 review

Malaria rapid diagnostic test (mRDT) vs clinical diagnosis

Antibiotic prescribing to microscopy‐ or PCR‐negative people · people with suspected malaria

Malaria rapid diagnostic test (mRDT) probably leads to higher antibiotic prescribing to microscopy‐ or PCR‐negative people compared with clinical diagnosis (moderate certainty).

1 finding from 1 review