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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,050 questions in 42 reviews · Incontinence

current versions
No studies 391 · 37.2%Ungraded 82 · 7.8%Very low 199 · 19%Low 206 · 19.6%Moderate 150 · 14.3%High 22 · 2.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Alarm vs other types of alarm
Proportion of children with adverse events ‐ code‐word alarm versus control alarm · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 1.34 [0.75, 2.38]1 study · 353 participantsModerate
Alarm vs other behavioural interventions
Mean number of wet nights a week · children with nocturnal enuresis in children
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
no estimate extracted3 studies · 95 participantsLow
Alarm vs other behavioural interventions
Proportion of children achieving 14 consecutive dry nights by the end of treatment · children with nocturnal enuresis in children
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 1.77 [0.98, 3.19]6 studies · 179 participantsLow
Alarm vs control or no treatment
Proportion of children dry at · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 9.67 [4.74, 19.76]10 studies · 366 participantsLow
Alarm vs other behavioural interventions
Proportion of children dry at · children with nocturnal enuresis in children
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 1.39 [0.81, 2.41]3 studies · 89 participantsLow
Alarm vs other behavioural interventions
Proportion of children with adverse events · children with nocturnal enuresis in children
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
no estimate extractedNRNo studies
Alarm vs desmopressin
Mean number of wet nights a week · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
no estimate extracted4 studies · 285 participantsLow
Alarm vs desmopressin
Proportion of children achieving 14 consecutive dry nights by the end of treatment · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 1.12 [0.93, 1.36]12 studies · 1168 participantsLow
Alarm vs desmopressin
Proportion of children dry at · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 1.3 [0.92, 1.84]5 studies · 565 participantsModerate
Alarm vs desmopressin
Proportion of children with adverse events · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 0.38 [0.2, 0.71]5 studies · 565 participantsModerate
Alarm vs tricyclics
Mean number of wet nights a week · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
no estimate extracted1 study · 29 participantsVery low
Alarm vs tricyclics
Proportion of children achieving 14 consecutive dry nights by the end of treatment · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 2.05 [1.33, 3.17]3 studies · 208 participantsVery low
Alarm vs tricyclics
Proportion of children dry at · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 11 [0.67, 179.29]1 study · 24 participantsVery low
Alarm vs tricyclics
Proportion of children with adverse events · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
no estimate extracted1 study · 1 participantsUngraded
Alarm vs control or no treatment
Proportion of children with adverse events · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
no estimate extractedNRNo studies
Alarm vs miscellaneous treatments
Mean number of wet nights a week ‐ alarm versus cognitive behavioural therapy · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
no estimate extracted1 study · 33 participantsVery low
Alarm vs miscellaneous treatments
Proportion of children achieving 14 consecutive dry nights by the end of treatment ‐ alarm versus cognitive behavioural therapy · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 0.84 [0.55, 1.29]1 study · 39 participantsVery low
Alarm vs miscellaneous treatments
Proportion of children dry at · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 0.48 [0.25, 0.92]1 study · 33 participantsVery low
Alarm vs miscellaneous treatments
Proportion of children achieving 14 consecutive dry nights by the end of treatment ‐ alarm versus psychotherapy · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 3.62 [1.38, 9.5]2 studies · 116 participantsVery low
Alarm vs miscellaneous treatments
Proportion of children achieving 14 consecutive dry nights by the end of treatment ‐ alarm versus hypnotherapy · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 3 [1.41, 6.39]1 study · 96 participantsVery low
Alarm vs miscellaneous treatments
Proportion of children dry at · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 3 [1.18, 7.6]1 study · 96 participantsVery low
Alarm vs miscellaneous treatments
Proportion of children achieving 14 consecutive dry nights by the end of treatment ‐ alarm versus restricted diet · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 23 [3.19, 165.98]1 study · 150 participantsVery low
Alarm vs miscellaneous treatments
Proportion of children adverse events · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
no estimate extractedNRNo studies
Alarm plus other intervention vs other intervention
Mean number of wet nights a week ‐ alarm + bladder training versus bladder training · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
no estimate extracted1 study · 22 participantsVery low
Alarm plus other intervention vs other intervention
Proportion of children achieving 14 consecutive dry nights by the end of treatment ‐ alarm + bladder training versus bladder training · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 3 [0.73, 12.27]1 study · 22 participantsVery low
Alarm vs placebo drug
Mean number of wet nights a week · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
no estimate extracted1 study · 47 participantsVery low
Alarm plus other intervention vs other intervention
Proportion of children achieving 14 consecutive dry nights by the end of treatment ‐ alarm + dry‐bed training versus dry‐bed training · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 3.79 [1.85, 7.77]1 study · 80 participantsLow
Alarm plus other intervention vs other intervention
Proportion of children dry at · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 0.56 [0.15, 2.12]1 study · 80 participantsLow
Alarm plus other intervention vs other intervention
Mean number of wet nights a week ‐ alarm + desmopressin versus desmopressin · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
no estimate extracted2 studies · 156 participantsLow
Alarm plus other intervention vs other intervention
Proportion of children achieving 14 consecutive dry nights by the end of treatment ‐ alarm + desmopressin versus desmopressin · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 1.32 [1.08, 1.62]5 studies · 359 participantsLow
Alarm plus other intervention vs other intervention
Proportion of children dry at · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 2.33 [1.26, 4.29]2 studies · 161 participantsLow
Alarm plus other intervention vs other intervention
Proportion of children with adverse events · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
no estimate extracted1 study · 1 participantsUngraded
Alarm vs placebo drug
Proportion of children achieving 14 consecutive dry nights by the end of treatment · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 1.59 [1.16, 2.17]2 studies · 181 participantsLow
Alarm vs placebo drug
Proportion of children dry at · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
no estimate extractedNRNo studies
Alarm vs placebo drug
Proportion of children with adverse events · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
no estimate extracted2 studies · 2 participantsUngraded
Alarm vs other types of alarm
Proportion of children achieving 14 consecutive dry nights by the end of treatment ‐ bell and pad versus body‐worn alarm · children with nocturnal enuresis
Alarm interventions for nocturnal enuresis in children (2020) · Cochrane
RR 1 [0.67, 1.5]1 study · 40 participantsVery low
Any pessary vs control, waiting list or no active treatment
Perceived resolution of prolapse symptoms: ≥ 12 months · pelvic organ prolapse in women
Pessaries (mechanical devices) for managing pelvic organ prolapse in women (2020) · Cochrane
no estimate extractedNRNo studies
Any pessary vs pelvic floor muscle training (PFMT)
Cure or improvement of sexual problems (higher score = better sexual functioning) · pelvic organ prolapse in women
Pessaries (mechanical devices) for managing pelvic organ prolapse in women (2020) · Cochrane
no estimate extracted1 study · 48 participantsLow
Any pessary vs pelvic floor muscle training (PFMT)
Psychological outcome measures at ≥ 12 months · pelvic organ prolapse in women
Pessaries (mechanical devices) for managing pelvic organ prolapse in women (2020) · Cochrane
no estimate extractedNRNo studies
Any pessary vs pelvic floor muscle training (PFMT)
Number of women with adverse events · pelvic organ prolapse in women
Pessaries (mechanical devices) for managing pelvic organ prolapse in women (2020) · Cochrane
RR 75.25 [4.7, 1205.45]1 study · 97 participantsLow
Pessary plus PFMT vs pelvic floor muscle training (PFMT) alone
Perceived resolution of prolapse symptoms ≥ 12 months · pelvic organ prolapse in women
Pessaries (mechanical devices) for managing pelvic organ prolapse in women (2020) · Cochrane
no estimate extractedNRNo studies
Pessary plus PFMT vs pelvic floor muscle training (PFMT) alone
Perceived improvement of prolapse symptoms · pelvic organ prolapse in women
Pessaries (mechanical devices) for managing pelvic organ prolapse in women (2020) · Cochrane
RR 2.15 [1.58, 2.94]1 study · 260 participantsModerate
Pessary plus PFMT vs pelvic floor muscle training (PFMT) alone
Prolapse‐specific quality of life · pelvic organ prolapse in women
Pessaries (mechanical devices) for managing pelvic organ prolapse in women (2020) · Cochrane
no estimate extracted1 study · 260 participantsModerate
Pessary plus PFMT vs pelvic floor muscle training (PFMT) alone
Cure or improvement of sexual problems ≥ 12 months · pelvic organ prolapse in women
Pessaries (mechanical devices) for managing pelvic organ prolapse in women (2020) · Cochrane
no estimate extractedNRNo studies
Pessary plus PFMT vs pelvic floor muscle training (PFMT) alone
Psychological outcome measures at ≥ 12 months · pelvic organ prolapse in women
Pessaries (mechanical devices) for managing pelvic organ prolapse in women (2020) · Cochrane
no estimate extractedNRNo studies
Pessary plus PFMT vs pelvic floor muscle training (PFMT) alone
Number of women with adverse events ‐ abnormal vaginal bleeding · pelvic organ prolapse in women
Pessaries (mechanical devices) for managing pelvic organ prolapse in women (2020) · Cochrane
RR 2.18 [0.69, 6.91]1 study · 260 participantsLow
Pessary plus PFMT vs pelvic floor muscle training (PFMT) alone
Number of women with adverse events ‐ de novo voiding difficulty · pelvic organ prolapse in women
Pessaries (mechanical devices) for managing pelvic organ prolapse in women (2020) · Cochrane
RR 1.32 [0.54, 3.19]1 study · 189 participantsLow
Any pessary vs control, waiting list or no active treatment
Perceived improvement of prolapse symptoms (higher score = worse symptoms) · pelvic organ prolapse in women
Pessaries (mechanical devices) for managing pelvic organ prolapse in women (2020) · Cochrane
no estimate extracted1 study · 27 participantsVery low
Any pessary vs control, waiting list or no active treatment
Prolapse‐specific quality of life ≥ 12 months · pelvic organ prolapse in women
Pessaries (mechanical devices) for managing pelvic organ prolapse in women (2020) · Cochrane
no estimate extractedNRNo studies
Any pessary vs control, waiting list or no active treatment
Cure or improvement of sexual problems · pelvic organ prolapse in women
Pessaries (mechanical devices) for managing pelvic organ prolapse in women (2020) · Cochrane
no estimate extracted1 study · 27 participantsVery low