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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,050 questions in 42 reviews · Incontinence

current versions
No studies 391 · 37.2%Ungraded 82 · 7.8%Very low 199 · 19%Low 206 · 19.6%Moderate 150 · 14.3%High 22 · 2.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Transvaginal permanent mesh vs native tissue repair
Awareness of prolapse (0.5 to 7 years) · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
RR 0.83 [0.73, 0.95]17 studies · 2932 participantsModerate
Transvaginal biological graft vs native tissue repair
Surgery for recurrent prolapse (1 to 2 years) · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
RR 1.15 [0.75, 1.77]6 studies · 899 participantsModerate
Transvaginal biological graft vs native tissue repair
Recurrent prolapse on examination · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
RR 0.96 [0.71, 1.29]9 studies · 1278 participantsLow
Transvaginal biological graft vs native tissue repair
Visceral injury · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
RR 0.34 [0.04, 3.26]2 studies · 254 participantsLow
Transvaginal biological graft vs native tissue repair
Bladder function · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
RR 12.64 [1.6, 100.06]2 studies · 143 participantsVery low
Transvaginal biological graft vs native tissue repair
Painful intercourse ‐ de novo dyspareunia · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
RR 1.3 [0.46, 3.66]2 studies · 125 participantsModerate
Transvaginal biological graft vs native tissue repair
Quality of life · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
no estimate extracted3 studies · 112 participantsVery low
Transvaginal permanent mesh vs native tissue repair
Repeat surgery (0.5 to 7 years) · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
RR 1.56 [1.07, 2.26]27 studies · 3916 participantsLow
Transvaginal permanent mesh vs native tissue repair
Recurrent prolapse on examination (any compartment) · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
RR 0.42 [0.32, 0.55]25 studies · 3680 participantsVery low
Transvaginal permanent mesh vs native tissue repair
Visceral injury · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
RR 3.67 [1.63, 8.28]14 studies · 1997 participantsLow
Transvaginal permanent mesh vs native tissue repair
Mesh exposure · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
RR 11.1 [6.81, 18.1]26 studies · 2980 participantsModerate
Transvaginal permanent mesh vs native tissue repair
Bladder function · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
RR 1.5 [1.19, 1.88]17 studies · 2001 participantsModerate
Transvaginal permanent mesh vs native tissue repair
Painful intercourse ‐ de novo dyspareunia · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
RR 1.22 [0.83, 1.79]16 studies · 1308 participantsModerate
Transvaginal permanent mesh vs native tissue repair
Quality of life · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
no estimate extracted9 studies · 1365 participantsVery low
Transvaginal biological graft vs native tissue repair
Awareness of prolapse (1 to 3 years) · vaginal prolapse
Transvaginal mesh or grafts or native tissue repair for vaginal prolapse (2024) · Cochrane
RR 1.06 [0.73, 1.56]8 studies · 1374 participantsModerate
Anticholinergics vs placebo
Mean change from baseline in condition‐specific quality of lifeScale from: ‐100 to 0 · adults with overactive bladder syndrome
Oral anticholinergic drugs versus placebo or no treatment for managing overactive bladder syndrome in adults (2023) · Cochrane
MD 4.4112 studies · 6804 participantsLow
Anticholinergics vs placebo
Patient perception of cure or improvement · adults with overactive bladder syndrome
Oral anticholinergic drugs versus placebo or no treatment for managing overactive bladder syndrome in adults (2023) · Cochrane
RR 1.38 [1.15, 1.66]9 studies · 8457 participantsModerate
Anticholinergics vs placebo
Mean number of urgency episodes per 24 hours · adults with overactive bladder syndrome
Oral anticholinergic drugs versus placebo or no treatment for managing overactive bladder syndrome in adults (2023) · Cochrane
MD 0.8523 studies · 16875 participantsModerate
Anticholinergics vs placebo
Adverse events: dry mouth · adults with overactive bladder syndrome
Oral anticholinergic drugs versus placebo or no treatment for managing overactive bladder syndrome in adults (2023) · Cochrane
RR 3.5 [3.26, 3.75]66 studies · 38368 participantsLow
Anticholinergics vs placebo
Adverse events:urinary retention · adults with overactive bladder syndrome
Oral anticholinergic drugs versus placebo or no treatment for managing overactive bladder syndrome in adults (2023) · Cochrane
RR 3.52 [2.04, 6.08]17 studies · 7862 participantsLow
Anticholinergics vs placebo
Withdrawal due to adverse events · adults with overactive bladder syndrome
Oral anticholinergic drugs versus placebo or no treatment for managing overactive bladder syndrome in adults (2023) · Cochrane
RR 1.37 [1.21, 1.56]61 studies · 36943 participantsLow
Anticholinergics vs placebo
Mean number of micturitions per 24 hours · adults with overactive bladder syndrome
Oral anticholinergic drugs versus placebo or no treatment for managing overactive bladder syndrome in adults (2023) · Cochrane
MD 0.8530 studies · 19395 participantsModerate
Single‐incision slings vs autologous fascial slings
Subjective cure or improvement of urinary incontinence: at 12 months · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
no estimate extractedNRNo studies
Single‐incision slings vs retropubic minimally‐invasive slings
Number of women with dyspareunia · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
no estimate extractedNRNo studies
Single‐incision slings vs retropubic minimally‐invasive slings
Number of women with mesh exposure, extrusion or erosion in any area · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
RR 1.55 [0.24, 9.82]3 studies · 267 participantsLow
Single‐incision slings vs retropubic minimally‐invasive slings
Number of women with urinary retention · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
RR 0.47 [0.12, 1.84]2 studies · 209 participantsLow
Single‐incision slings vs retropubic minimally‐invasive slings
Quality of life: at 12 months · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
no estimate extractedNRNo studies
Single‐incision slings vs retropubic minimally‐invasive slings
Number of women requiring repeat continence surgery or mesh revision · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
RR 4.19 [0.31, 57.28]2 studies · 182 participantsVery low
Single‐incision slings vs transobturator minimally‐invasive slings
Subjective cure or improvement of urinary incontinence: 12 months · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
RR 1 [0.97, 1.03]17 studies · 2359 participantsHigh
Single‐incision slings vs transobturator minimally‐invasive slings
Patient‐reported pain: at more than 24 months · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
RR 0.12 [0.02, 0.68]2 studies · 250 participantsModerate
Single‐incision slings vs transobturator minimally‐invasive slings
Number of women with dyspareunia · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
RR 0.78 [0.41, 1.48]8 studies · 810 participantsModerate
Single‐incision slings vs transobturator minimally‐invasive slings
Number of women with mesh exposure, extrusion or erosion in any area · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
RR 0.61 [0.39, 0.96]16 studies · 2378 participantsHigh
Single‐incision slings vs transobturator minimally‐invasive slings
Number of women with urinary retention · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
RR 0.68 [0.47, 0.97]23 studies · 2891 participantsModerate
Single‐incision slings vs autologous fascial slings
Patient‐reported pain: at more than 24 months · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
no estimate extractedNRNo studies
Single‐incision slings vs transobturator minimally‐invasive slings
Quality of life: at 12 months · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
SMD 0.24 [0.09, 0.39]8 studies · 689 participantsLow
Single‐incision slings vs transobturator minimally‐invasive slings
Number of women requiring repeat continence surgery or mesh revision · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
RR 1.42 [0.94, 2.16]13 studies · 1460 participantsLow
Single‐incision slings vs autologous fascial slings
Number of women with dyspareunia · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
RR 1.33 [0.32, 5.53]1 study · 70 participantsLow
Single‐incision slings vs autologous fascial slings
Number of women with mesh exposure, extrusion or erosion in any area · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
RR 2 [0.19, 21.06]1 study · 70 participantsLow
Single‐incision slings vs autologous fascial slings
Number of women with urinary retention · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
no estimate extractedNRNo studies
Single‐incision slings vs autologous fascial slings
Quality of life: at 12 months · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
no estimate extractedNRNo studies
Single‐incision slings vs autologous fascial slings
Number of women requiring repeat continence surgery · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
no estimate extractedNRNo studies
Single‐incision slings vs retropubic minimally‐invasive slings
Subjective cure or improvement of urinary incontinence: at 12 months · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
RR 0.99 [0.91, 1.07]2 studies · 297 participantsLow
Single‐incision slings vs retropubic minimally‐invasive slings
Patient‐reported pain: at more than 24 months · women with urinary incontinence
Single‐incision sling operations for urinary incontinence in women (2023) · Cochrane
no estimate extractedNRNo studies
Vaginal procedure vs sacral colpopexy (vault prolapse)
Awareness of prolapse · women with apical vaginal vault prolapse
Surgery for women with apical vaginal prolapse (2023) · Cochrane
RR 2.31 [1.27, 4.21]4 studies · 346 participantsModerate
Vaginal hysterectomy vs sacral hysteropexy/cervicopexy (uterine prolapse)
Surgery for recurrent prolapse · women with apical uterine prolapse
Surgery for women with apical vaginal prolapse (2023) · Cochrane
RR 0.85 [0.47, 1.54]5 studies · 403 participantsLow
Vaginal hysterectomy vs sacral hysteropexy/cervicopexy (uterine prolapse)
Prolapse on examination (Stage 2 or greater) ‐ Any recurrent prolapse · women with apical uterine prolapse
Surgery for women with apical vaginal prolapse (2023) · Cochrane
RR 0.78 [0.54, 1.11]2 studies · 230 participantsModerate
Vaginal hysterectomy vs sacral hysteropexy/cervicopexy (uterine prolapse)
Mesh exposure · women with apical uterine prolapse
Surgery for women with apical vaginal prolapse (2023) · Cochrane
RR 1.85 [0.7, 4.87]4 studies · 307 participantsVery low
Vaginal hysterectomy vs sacral hysteropexy/cervicopexy (uterine prolapse)
Operating time (minutes) · women with apical uterine prolapse
Surgery for women with apical vaginal prolapse (2023) · Cochrane
no estimate extracted5 studies · 422 participantsLow
Vaginal hysterectomy vs sacral hysteropexy/cervicopexy (uterine prolapse)
Length of Hospital Stay (days) · women with apical uterine prolapse
Surgery for women with apical vaginal prolapse (2023) · Cochrane
no estimate extracted5 studies · 422 participantsVery low
Vaginal hysterectomy vs sacral hysteropexy/cervicopexy (uterine prolapse)
Blood loss (mls) · women with apical uterine prolapse
Surgery for women with apical vaginal prolapse (2023) · Cochrane
no estimate extracted2 studies · 148 participantsLow