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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,852 questions in 128 reviews · Effective Practice and Organisation of Care

current versions
No studies 557 · 30.1%Ungraded 53 · 2.9%Very low 446 · 24.1%Low 476 · 25.7%Moderate 255 · 13.8%High 65 · 3.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Early warning systems (EWS) and rapid response systems (RRS) vs usual care
Hospital mortality – randomised trials ( · adult on acute hospital wards at risk of clinical deterioration
Early warning systems and rapid response systems for the prevention of patient deterioration on acute adult… (2021) · Cochrane
AOR 0.52 [0.32, 0.85]2792 participantsLow
Early warning systems (EWS) and rapid response systems (RRS) vs usual care
Length of hospital stay – non‐randomised studies · adult on acute hospital wards at risk of clinical deterioration
Early warning systems and rapid response systems for the prevention of patient deterioration on acute adult… (2021) · Cochrane
no estimate extractedNRNo studies
Early warning systems (EWS) and rapid response systems (RRS) vs usual care
Adverse events (unexpected cardiac or respiratory arrest) – randomised trials ( · adult on acute hospital wards at risk of clinical deterioration
Early warning systems and rapid response systems for the prevention of patient deterioration on acute adult… (2021) · Cochrane
AOR 0.94 [0.79, 1.13]364094 participantsLow
Early warning systems (EWS) and rapid response systems (RRS) vs usual care
Adverse events (unexpected cardiac or respiratory arrest) – non‐randomised studies ( · adult on acute hospital wards at risk of clinical deterioration
Early warning systems and rapid response systems for the prevention of patient deterioration on acute adult… (2021) · Cochrane
no estimate extractedNRVery low
Early warning systems (EWS) and rapid response systems (RRS) vs usual care
Hospital mortality – non‐randomised studies ( · adult on acute hospital wards at risk of clinical deterioration
Early warning systems and rapid response systems for the prevention of patient deterioration on acute adult… (2021) · Cochrane
no estimate extractedNRVery low
Early warning systems (EWS) and rapid response systems (RRS) vs usual care
Composite outcome – randomised trials Composite outcome of incidence (events divided by number of eligible participants admitted to the hospital during the study period) of cardiac arrests without a pre‐existing NFR order, unplanned ICU admissions... · adult on acute hospital wards at risk of clinical deterioration
Early warning systems and rapid response systems for the prevention of patient deterioration on acute adult… (2021) · Cochrane
AOR 0.98 [0.83, 1.16]364094 participantsModerate
Early warning systems (EWS) and rapid response systems (RRS) vs usual care
Composite outcome – non‐randomised studies Composite endpoint of cardiopulmonary arrest, unplanned ICU admission or death per 1000 admitted patients ( · adult on acute hospital wards at risk of clinical deterioration
Early warning systems and rapid response systems for the prevention of patient deterioration on acute adult… (2021) · Cochrane
AOR 0.85 [0.72, 0.99]57858 participantsLow
Early warning systems (EWS) and rapid response systems (RRS) vs usual care
Unplanned ICU admission – randomised trials ( · adult on acute hospital wards at risk of clinical deterioration
Early warning systems and rapid response systems for the prevention of patient deterioration on acute adult… (2021) · Cochrane
AOR 1.04 [0.89, 1.21]364094 participantsLow
Early warning systems (EWS) and rapid response systems (RRS) vs usual care
Unplanned ICU admission – non‐randomised trial ( · adult on acute hospital wards at risk of clinical deterioration
Early warning systems and rapid response systems for the prevention of patient deterioration on acute adult… (2021) · Cochrane
no estimate extractedNRVery low
Early warning systems (EWS) and rapid response systems (RRS) vs usual care
ICU readmission – randomised trials · adult on acute hospital wards at risk of clinical deterioration
Early warning systems and rapid response systems for the prevention of patient deterioration on acute adult… (2021) · Cochrane
no estimate extractedNRNo studies
Early warning systems (EWS) and rapid response systems (RRS) vs usual care
ICU readmission – non‐randomised studies · adult on acute hospital wards at risk of clinical deterioration
Early warning systems and rapid response systems for the prevention of patient deterioration on acute adult… (2021) · Cochrane
no estimate extractedNRNo studies
Early warning systems (EWS) and rapid response systems (RRS) vs usual care
Length of hospital stay – randomised trials ( · adult on acute hospital wards at risk of clinical deterioration
Early warning systems and rapid response systems for the prevention of patient deterioration on acute adult… (2021) · Cochrane
HR 0.91 [0.83, 0.98]2733 participantsLow
Intervention NR
Clinical outcomes · Adults with multimorbidity (two or more chronic conditions)
Interventions for improving outcomes in patients with multimorbidity in primary care and community settings (2021) · Cochrane
no estimate extractedNRModerate
Intervention NR
Mental health outcomes · Adults with multimorbidity (two or more chronic conditions)
Interventions for improving outcomes in patients with multimorbidity in primary care and community settings (2021) · Cochrane
no estimate extractedNRHigh
Intervention NR
Patient‐reported outcome measures (PROMs) · Adults with multimorbidity (two or more chronic conditions)
Interventions for improving outcomes in patients with multimorbidity in primary care and community settings (2021) · Cochrane
no estimate extractedNRModerate
Intervention NR
Health Service Utilisation · Adults with multimorbidity (two or more chronic conditions)
Interventions for improving outcomes in patients with multimorbidity in primary care and community settings (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Medication use and adherence · Adults with multimorbidity (two or more chronic conditions)
Interventions for improving outcomes in patients with multimorbidity in primary care and community settings (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Health‐related patient behaviours · Adults with multimorbidity (two or more chronic conditions)
Interventions for improving outcomes in patients with multimorbidity in primary care and community settings (2021) · Cochrane
no estimate extractedNRModerate
Intervention NR
Provider behaviour · Adults with multimorbidity (two or more chronic conditions)
Interventions for improving outcomes in patients with multimorbidity in primary care and community settings (2021) · Cochrane
no estimate extractedNRModerate
Intervention NR
Primary outcomes
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Impacts on management or information systems (if not a targeted measure of performance)
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Equity considerations: evidence of differential impacts on different parts of the population
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Primary outcomes
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Health outcomes
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Delivery and utilization of health services
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Quality of care
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Unintended effectsÂ
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Changes in resource use
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Secondary outcomes
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Provider motivation, satisfaction, absenteeism and acceptability
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Health outcomes
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Patient satisfaction and acceptability
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Impacts on management or information systems (if not a targeted measure of performance)
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Equity considerations: evidence of differential impacts on different parts of the population
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Delivery and utilization of health services
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Quality of care
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Unintended effects
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Resource use
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Secondary outcomes
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Provider motivation, satisfaction, absenteeism and acceptability
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Intervention NR
Patient satisfaction and acceptability
Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries (2021) · Cochrane
no estimate extractedNRLow
Lay health worker‐led psychological interventions vs usual care
Recovery from CMDs ‐ intermediate term (1 to 6 months post intervention) Recovery defined by HDRS < 8a; SRQ‐20 ≤ 7b (RR > 1 denotes greater likelihood of recovery) · adults with common mental disorders (CMDs)
Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐… (2021) · Cochrane
RR 1.29 [1.06, 1.56]2 studies · 308 participantsLow
Primary‐level worker‐led collaborative care vs usual care
CMD symptoms ‐ intermediate term (1 to 6 months post intervention) Measured by change in CIS‐Rg; GHQ‐12i; HDRSc; PHQ‐9e,j,k scores from baseline (greater decline = greater improvement) · adults with common mental disorders
Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐… (2021) · Cochrane
no estimate extracted6 studies · 4419 participantsLow
Primary health professionals and lay health workers vs usual care
Quality of life (carer) (1 to 6 months post intervention) WHOQOL‐BREF (higher score = better quality of life) · people with dementia and their carers
Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐… (2021) · Cochrane
no estimate extracted1 study · 53 participantsVery low
Primary health professionals and lay health workers vs usual care
Functional impairment (patient) (1 to 6 months post intervention) EASI (higher score = higher impairment in activities of daily living) · people with dementia and their carers
Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐… (2021) · Cochrane
no estimate extracted1 study · 81 participantsVery low
Primary health professionals and lay health workers vs usual care
Service utilisation ‐ home visits by LHW and psychiatrist (during intervention) · people with dementia and their carers
Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐… (2021) · Cochrane
no estimate extracted1 study · 81 participantsVery low
Primary health professionals and lay health workers vs usual care
Adverse events ‐ number of deaths (during intervention) Â · people with dementia and their carers
Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐… (2021) · Cochrane
no estimate extracted2 studies · 141 participantsVery low
Lay health worker‐led psychosocial interventions vs usual or no care
Depression or PTSD recovery · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms
Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐… (2021) · Cochrane
no estimate extractedNRNo studies
Lay health worker‐led psychosocial interventions vs usual or no care
Disease prevalence · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms
Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐… (2021) · Cochrane
no estimate extractedNRNo studies
Lay health worker‐led psychosocial interventions vs usual or no care
Depression symptoms (1 to 6 months post intervention) Depression self‐rating scale (higher score = higher severity) · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms
Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐… (2021) · Cochrane
no estimate extracted3 studies · 1092 participantsModerate