Suspected ototoxicity · people (of any age) with CSOM
1 finding from 1 review
Resolution of ear discharge ‐ measured at 1 to 2 weeks · adults with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Resolution of ear discharge ‐ measured after 4 weeks · adults with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Presence of dry socket · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
Systemic antibiotic prophylaxis (any regimen; topical therapy… may leads to lower dry socket compared with placebo (low certainty).
1 finding from 1 review
Infectious complications · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
Systemic antibiotic prophylaxis (any regimen; topical therapy… may leads to lower postsurgical infectious complications compared with placebo (low certainty).
1 finding from 1 review
Swelling (7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes swelling (7th day) compared with placebo (very low certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes pain (continuous, VAS 0-10 cm, 7th day) compared with placebo (very low certainty).
1 finding from 1 review
Pain (dichotomous, present/absent on 6th-7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes presence of pain (dichotomous, yes/no on 6th-7th day) compared with placebo (very low certainty).
1 finding from 1 review
Adverse effects · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes adverse effects compared with placebo (very low certainty).
1 finding from 1 review
Trismus (dichotomous, 7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes trismus (dichotomous, 7th day) compared with placebo (very low certainty).
1 finding from 1 review
Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs Placebo
Outcome not reported · Immunosuppressed / immunocompromised patients (e.g. HIV infection, AIDS, diabetes, transplants) undergoing tooth extraction
The review found no eligible studies for this question.
1 finding from 1 review
Fever · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes fever (6th-7th day) compared with placebo (very low certainty).
1 finding from 1 review
Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs Placebo
Outcome not reported · Patients undergoing tooth extraction for severe dental caries or periodontal disease in general dental practice (non-third-molar / decayed…
The review found no eligible studies for this question.
1 finding from 1 review
Intervention not reported
Treatment 2: topical regimen alone (chloramphenicol‐sulfadimidine) · participants undergoing cataract surgery
1 finding from 1 review
no estimate extracted
6618 participants
Moderate
Intervention not reported
Treatment 1: fixed combination of topical gatifloxacin 0.3% and prednisolone acetate 1% · participants undergoing cataract surgery
1 finding from 1 review
no estimate extracted
108 participants
Very low
Intervention not reported
Treatment 2: individual instillation of topical gatifloxacin 0.3% and prednisolone acetate 1% · participants undergoing cataract surgery
1 finding from 1 review
no estimate extracted
108 participants
Very low
Intervention not reported
Treatment 1: combined intracameral cefuroxime and topical levofloxacin · participants undergoing cataract surgery
1 finding from 1 review
no estimate extracted
16603 participants
High
Intervention not reported
Treatment 3: topical levofloxacin 0.5% · participants undergoing cataract surgery
1 finding from 1 review
no estimate extracted
16603 participants
Moderate
Intervention not reported
Treatment 1: combined prophylaxis (topical regimen + periocular penicillin at the time of surgery) · participants undergoing cataract surgery
1 finding from 1 review
no estimate extracted
6618 participants
Moderate
Resolution of hordeolum at short term · people with acute hordeolum
Acupuncture may leads to higher resolution of hordeolum at short term compared with topical antibiotics (low certainty).
1 finding from 1 review