Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

275 questions · 279 findings · 32 reviews · Kidney and Transplant

No studies found 76 · 27.2%GRADE not reported 5 · 1.8%Very low 42 · 15.1%Low 105 · 37.6%Moderate 46 · 16.5%High 5 · 1.8%

Dual therapy (angiotensin‐converting‐enzyme inhibitors plus angiotensin receptor blockers) vs placebo or no treatment

Fatal or nonfatal myocardial infarction · people with diabetes and kidney disease

The review found no eligible studies for this question.

1 finding from 1 review

Dual therapy (angiotensin‐converting‐enzyme inhibitors plus angiotensin receptor blockers) vs placebo or no treatment

Micro‐ to normoalbuminuria6 · people with diabetes and kidney disease

It is very uncertain whether dual therapy (angiotensin‐converting‐enzyme inhibitors plus… changes micro‐ to normoalbuminuria6 compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Fixed reduction of dialysate temperature vs standard dialysate temperature

Intradialytic hypotension rate · patients requiring haemodialysis

It is very uncertain whether fixed reduction of dialysate temperature changes intradialytic hypotension rate compared with standard dialysate temperature (very low certainty).

1 finding from 1 review

Isothermal dialysate vs thermoneutral dialysate

Intradialytic hypotension rate · patients requiring haemodialysis

It is very uncertain whether isothermal dialysate changes intradialytic hypotension rate compared with thermoneutral dialysate (very low certainty).

1 finding from 1 review