Very potent vs potent topical corticosteroid
- Strategies for using topical corticosteroids in children and adults with eczema 2022 · Cochrane Headline outcomes onlyno estimate extracted1 study · 117 participantsVery low
It is very uncertain whether weekend therapy changes systemic adverse events: abnormal cortisol; end of treatment (16… compared with no topical corticosteroid (very low certainty).
It is very uncertain whether moderate‐potency changes systemic adverse events: abnormal cortisol; end of treatment (6‐28… compared with mild‐potency topical corticosteroid (very low certainty).
The intervention showed no clear difference in number of participants with exacerbations requiring systemic steroids (moderate certainty).
The intervention showed no clear difference in number of participants with exacerbations requiring systemic steroids (moderate certainty).
ICS showed no clear difference in hospital admission compared with systemic corticosteroids (low certainty).
Inhaled steroids showed no clear difference in death or BPD at 36 weeks' postmenstrual age compared with systemic steroids (moderate certainty).
Inhaled steroids probably leads to lower diastolic blood pressure > 95th percentile at 7 years compared with systemic steroids (moderate certainty).
Inhaled steroids showed no clear difference in ever diagnosed as asthmatic by 7 years compared with systemic steroids (moderate certainty).
Inhaled steroids showed no clear difference in BPD at 36 weeks' postmenstrual age compared with systemic steroids (low certainty).
Inhaled steroids showed no clear difference in hyperglycaemia compared with systemic steroids (low certainty).
Inhaled steroids may leads to lower hypertension compared with systemic steroids (low certainty).
Inhaled steroids showed no clear difference in general conceptual ability (GCA) score at 7 years The test has a… compared with systemic steroids (moderate certainty).
Inhaled steroids showed no clear difference in moderate/severe disability at 7 years compared with systemic steroids (moderate certainty).
Inhaled steroids showed no clear difference in death or moderate/severe disability at 7 years compared with systemic steroids (moderate certainty).
Inhaled steroids showed no clear difference in systolic blood pressure > 95th percentile at 7 years compared with systemic steroids (moderate certainty).
The review found no eligible studies for this question.