Acute‐phase response · children with familial Mediterranean fever
1 finding from 1 review
No cure ‐ all trials · patients with asymptomatic bacteriuria during pregnancy
It is very uncertain whether single‐dose antibiotic changes no cure ‐ all trials compared with short‐course (four‐ to seven‐day) antibiotic (very low certainty).
1 finding from 1 review
Recurrent asymptomatic bacteriuria ‐ all trials · patients with asymptomatic bacteriuria during pregnancy
It is very uncertain whether single‐dose antibiotic changes recurrent asymptomatic bacteriuria ‐ all trials compared with short‐course (four‐ to seven‐day) antibiotic (very low certainty).
1 finding from 1 review
Pyelonephritis ‐ Same antimicrobial agent only4 · patients with asymptomatic bacteriuria during pregnancy
It is very uncertain whether single‐dose antibiotic changes pyelonephritis ‐ Same antimicrobial agent only4 compared with short‐course (four‐ to seven‐day) antibiotic (very low certainty).
1 finding from 1 review
Low birthweight ‐ Same antimicrobial agent only · patients with asymptomatic bacteriuria during pregnancy
Single‐dose antibiotic leads to higher low birthweight ‐ Same antimicrobial agent only compared with short‐course (four‐ to seven‐day) antibiotic (high certainty).
1 finding from 1 review
Preterm delivery ‐ Same antimicrobial agent only · patients with asymptomatic bacteriuria during pregnancy
Single‐dose antibiotic showed no clear difference in preterm delivery ‐ Same antimicrobial agent only compared with short‐course (four‐ to seven‐day) antibiotic (moderate certainty).
1 finding from 1 review
Side effects ‐ all trials · patients with asymptomatic bacteriuria during pregnancy
Single‐dose antibiotic may leads to lower side effects ‐ all trials compared with short‐course (four‐ to seven‐day) antibiotic (low certainty).
1 finding from 1 review
Same antimicrobial agent ‐ No cure (good quality studies) · patients with asymptomatic bacteriuria during pregnancy
Single‐dose antibiotic leads to higher same antimicrobial agent ‐ No cure (good quality studies) compared with short‐course (four‐ to seven‐day) antibiotic (high certainty).
1 finding from 1 review
Different antimicrobial agents ‐ No cure (good quality studies) · patients with asymptomatic bacteriuria during pregnancy
Single‐dose antibiotic showed no clear difference in different antimicrobial agents ‐ No cure (good quality studies) compared with short‐course (four‐ to seven‐day) antibiotic (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · adults with asthma not well controlled on ICS
Single inhaler therapy leads to lower discontinuation due to adverse events compared with fixed dose ICS (high certainty).
1 finding from 1 review
Hospital admissions due to exacerbations: number of participants · adults with asthma not well controlled on ICS
Single inhaler therapy showed no clear difference in patients with exacerbations causing hospitalisation compared with fixed dose ICS (moderate certainty).
1 finding from 1 review
Rate of exacerbations requiring systemic corticosteroids · adults with asthma not well controlled on ICS
Single inhaler therapy leads to lower patients with exacerbations treated with oral steroids compared with fixed dose ICS (high certainty).
1 finding from 1 review
Fatal serious adverse events · adults with asthma not well controlled on ICS
Single inhaler therapy showed no clear difference in fatal serious adverse events compared with fixed dose ICS (moderate certainty).
1 finding from 1 review
Non‐fatal serious adverse events · adults with asthma not well controlled on ICS
Single inhaler therapy showed no clear difference in serious adverse events (non‐fatal) compared with fixed dose ICS (moderate certainty).
1 finding from 1 review
Participants with a serious adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with ≥ 1 adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with a serious adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with ≥ 1 adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with a serious adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with ≥ 1 adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review