Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

480 questions · 494 findings · 38 reviews

No studies found 118 · 23.9%GRADE not reported 54 · 10.9%Very low 176 · 35.6%Low 99 · 20%Moderate 34 · 6.9%High 13 · 2.6%

RISPERIDONE vs COMBINATION: a. RISPERIDONE + OXCARBAZEPINE

Adverse effects ‐ movement disorders · psychosis‐induced aggression or agitation (rapid tranquillisation)

It is very uncertain whether RISPERIDONE changes adverse effects: movement disorders, over 24 hours compared with COMBINATION: a. RISPERIDONE + OXCARBAZEPINE (very low certainty).

1 finding from 1 review

RISPERIDONE vs COMBINATION: b. RISPERIDONE + VALPROIC ACID

Adverse effects ‐ movement disorders · psychosis‐induced aggression or agitation (rapid tranquillisation)

It is very uncertain whether RISPERIDONE changes adverse effects: movement disorders, over 24 hours compared with COMBINATION: b. RISPERIDONE + VALPROIC ACID (very low certainty).

1 finding from 1 review

RISPERIDONE vs haloperidol

Specific behaviour ‐ agitation · psychosis‐induced aggression or agitation (rapid tranquillisation)

It is very uncertain whether RISPERIDONE changes specific behaviour: agitation, up to 24 hours (PANSS‐PAS response) compared with OTHER ANTIPSYCHOTIC: a. HALOPERIDOL (very low certainty).

1 finding from 1 review

RISPERIDONE vs haloperidol

Global outcome: need for additional measures · psychosis‐induced aggression or agitation (rapid tranquillisation)

It is very uncertain whether RISPERIDONE changes global outcome: need for additional measures compared with OTHER ANTIPSYCHOTIC: a. HALOPERIDOL (very low certainty).

1 finding from 1 review