Findings

What do systematic reviews say?

681 questions · 709 findings · 179 reviews

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No studies found 180 · 25.4%GRADE not reported 51 · 7.2%Very low 194 · 27.4%Low 144 · 20.3%Moderate 110 · 15.5%High 30 · 4.2%

Selective serotonin reuptake inhibitors vs placebo

panic symptoms · adults with panic disorder

2 findings from 1 review

Antidepressants versus placebo for panic disorder in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1625 participants
Moderate
Antidepressants versus placebo for panic disorder in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 1255 participants
Moderate

Selective serotonin reuptake inhibitors vs placebo

Withdrawals due to adverse events · adults with panic disorder

Selective serotonin reuptake inhibitors probably leads to higher number of dropouts due to adverse effects compared with placebo (moderate certainty).

1 finding from 1 review

Antidepressants versus placebo for panic disorder in adults 2018 · Cochrane Headline outcomes only
RR 1.45 [1.16, 1.81]
22 studies · 4131 participants
Moderate

Selective serotonin reuptake inhibitors vs placebo

Subjective sleep quality or quantity · adults with insomnia

1 finding from 1 review

Antidepressants for insomnia in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 135 participants
Low

Selective serotonin reuptake inhibitors vs placebo

Other subjective measures of sleep (total sleep time, sleep onset latency, nocturnal awakenings and subjective sleep efficiency) (PSQI) (at 12 weeks) · adults with insomnia

1 finding from 1 review

Antidepressants for insomnia in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 27 participants
Very low

Selective serotonin reuptake inhibitors vs placebo

Adverse events (at 12 weeks) · adults with insomnia

1 finding from 1 review

Antidepressants for insomnia in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 27 participants
Very low

Selective serotonin reuptake inhibitors vs placebo

PSG sleep outcomes (at 12 weeks) · adults with insomnia

1 finding from 1 review

Antidepressants for insomnia in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Acceptance interventions for weight concern vs no weight management intervention

Change in weight (kg) · People wanting to quit smoking

3 findings from 1 review

Interventions for preventing weight gain after smoking cessation 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 169 participants
Very low
Interventions for preventing weight gain after smoking cessation 2021 · Cochrane Headline outcomes only
MD 0
3 studies · 106 participants
Low
Interventions for preventing weight gain after smoking cessation 2021 · Cochrane Headline outcomes only
MD 0.7
2 studies · 76 participants
Very low

Acceptance interventions for weight concern vs no weight management intervention

Smoking cessation · People wanting to quit smoking

Acceptance interventions for weight concern may leads to higher smoking cessation at 6 months compared with no weight management intervention (low certainty).

1 finding from 1 review

Interventions for preventing weight gain after smoking cessation 2021 · Cochrane Headline outcomes only
RR 1.42 [1.03, 1.96]
4 studies · 619 participants
Low

Acceptance interventions for weight concern vs no weight management intervention

Behaviour change: smoking cessation · People wanting to quit smoking

Acceptance interventions for weight concern showed no clear difference in smoking cessation at 12 months compared with no weight management intervention (low certainty).

1 finding from 1 review

Interventions for preventing weight gain after smoking cessation 2021 · Cochrane Headline outcomes only
RR 1.25 [0.76, 2.06]
2 studies · 496 participants
Low

Serotonin and noradrenaline reuptake inhibitors (SNRI) vs placebo

Outcomes (2‐6 months post‐treatment) · adults with panic disorder

The review found no eligible studies for this question.

1 finding from 1 review

Antidepressants versus placebo for panic disorder in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Serotonin and noradrenaline reuptake inhibitors (SNRI) vs placebo

Failure to respond at endpoint (6‐12 weeks) · adults with panic disorder

Serotonin‐norepinephrine reuptake inhibitors may leads to lower failure to respond compared with placebo (low certainty).

1 finding from 1 review

Antidepressants versus placebo for panic disorder in adults 2018 · Cochrane Headline outcomes only
RR 0.61 [0.41, 0.91]
4 studies · 1531 participants
Low

Serotonin and noradrenaline reuptake inhibitors (SNRI) vs placebo

Leaving the study early · adults with panic disorder

Serotonin‐norepinephrine reuptake inhibitors showed no clear difference in total number of dropouts compared with placebo (moderate certainty).

1 finding from 1 review

Antidepressants versus placebo for panic disorder in adults 2018 · Cochrane Headline outcomes only
RR 0.93 [0.69, 1.26]
4 studies · 1531 participants
Moderate

Serotonin and noradrenaline reuptake inhibitors (SNRI) vs placebo

Failure to remit at endpoint · adults with panic disorder

Serotonin‐norepinephrine reuptake inhibitors probably leads to lower failure to remit compared with placebo (moderate certainty).

1 finding from 1 review

Antidepressants versus placebo for panic disorder in adults 2018 · Cochrane Headline outcomes only
RR 0.84 [0.75, 0.95]
4 studies · 1531 participants
Moderate

Serotonin and noradrenaline reuptake inhibitors (SNRI) vs placebo

panic symptoms · adults with panic disorder

2 findings from 1 review

Antidepressants versus placebo for panic disorder in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 723 participants
High
Antidepressants versus placebo for panic disorder in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 685 participants
High

Serotonin and noradrenaline reuptake inhibitors (SNRI) vs placebo

Withdrawals due to adverse events · adults with panic disorder

Serotonin‐norepinephrine reuptake inhibitors showed no clear difference in number of dropouts due to adverse effects compared with placebo (moderate certainty).

1 finding from 1 review

Antidepressants versus placebo for panic disorder in adults 2018 · Cochrane Headline outcomes only
RR 1.49 [0.92, 2.4]
4 studies · 1531 participants
Moderate

Prism adaptation test with eye muscle surgery vs eye muscle surgery alone

Motor alignment at near fixation Measured using PACT at 6 months · people with intermittent exotropia, aged 5 to 49 years

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for intermittent exotropia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prism adaptation test with eye muscle surgery vs eye muscle surgery alone

Stereoacuity at near · people with intermittent exotropia, aged 5 to 49 years

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for intermittent exotropia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prism adaptation test with eye muscle surgery vs eye muscle surgery alone

Stereoacuity at distance · people with intermittent exotropia, aged 5 to 49 years

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for intermittent exotropia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prism adaptation test with eye muscle surgery vs eye muscle surgery alone

Motor alignment at distance fixation Measured using PACT at 6 months · people with intermittent exotropia, aged 5 to 49 years

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for intermittent exotropia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prism adaptation test with eye muscle surgery vs eye muscle surgery alone

Motor fusion test · people with intermittent exotropia, aged 5 to 49 years

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for intermittent exotropia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found