SAEs · people who smoke
It is very uncertain whether longer changes overall SAEs ‐ 26 weeks versus 8 weeks compared with shorter duration of combination nicotine replacement therapy (very low certainty).
3 findings from 1 review
RR 1.63 [0.6, 4.42]
1 study · 544 participants
Very low
no estimate extracted
1 study · 637 participants
Very low
no estimate extracted
1 study · 987 participants
Very low
Treatment withdrawal · people who smoke
1 finding from 1 review
Death at day 30Â · AKI
Early showed no clear difference in death at day 30Â compared with standard initiation of kidney replacement therapy (KRT) (low certainty).
1 finding from 1 review
Length of hospital stay · AKI
1 finding from 1 review
Death by AKI aetiology: non‐surgical causes · AKI
Subgroup analyses: early showed no clear difference in death by AKI aetiology: non‐surgical causes compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).
1 finding from 1 review
Death by AKI aetiology: surgical causes · AKI
Subgroup analyses: early showed no clear difference in death by AKI aetiology: surgical causes compared with standard initiation of kidney replacement therapy (KRT) (low certainty).
1 finding from 1 review
Kidney recovery functionby KRT: continuous KRT · AKI
Subgroup analyses: early showed no clear difference in kidney recovery functionby KRT: continuous KRT compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).
1 finding from 1 review
Kidney recovery functionby KRT: continuous and intermittent KRT · AKI
Subgroup analyses: early showed no clear difference in kidney recovery functionby KRT: continuous and intermittent KRT compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).
1 finding from 1 review
Death after 30 days · AKI
Early showed no clear difference in death after 30 days compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).
1 finding from 1 review
Death or non recovery kidney function at day 90 · AKI
Early showed no clear difference in death or non‐recovery of kidney function Time frame: day 90 compared with standard initiation of kidney replacement therapy (KRT) (low certainty).
1 finding from 1 review
Recovery of kidney function Patients free from KRT according to ITT analysis (all patients) · AKI
Early showed no clear difference in recovery of kidney function Patients free from KRT according to ITT… compared with standard initiation of kidney replacement therapy (KRT) (low certainty).
1 finding from 1 review
Adverse events: hypophosphataemia · AKI
Early leads to higher adverse events: hypophosphataemia compared with standard initiation of kidney replacement therapy (KRT) (high certainty).
1 finding from 1 review
Adverse events: hypotension · AKI
Early leads to higher adverse events: hypotension compared with standard initiation of kidney replacement therapy (KRT) (high certainty).
1 finding from 1 review
Adverse events: cardiac‐rhythm disorder · AKI
Early leads to higher adverse events: cardiac‐rhythm disorder compared with standard initiation of kidney replacement therapy (KRT) (high certainty).
1 finding from 1 review
Adverse events: infection · AKI
Early showed no clear difference in adverse events: infection compared with standard initiation of kidney replacement therapy (KRT) (high certainty).
1 finding from 1 review
Duration of ICU stay · AKI
1 finding from 1 review
Outcomes (up to 30 days' · adults with severe aortic stenosis who are at a low surgical risk.
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · adults with severe aortic stenosis who are at a low surgical risk.
Transcatheter aortic valve implantation showed no clear difference in all‐cause mortality compared with surgical aortic valve replacement (moderate certainty).
1 finding from 1 review
Stroke · adults with severe aortic stenosis who are at a low surgical risk.
Transcatheter aortic valve implantation showed no clear difference in stroke compared with surgical aortic valve replacement (moderate certainty).
1 finding from 1 review
Patient readmissions · adults with severe aortic stenosis who are at a low surgical risk.
Transcatheter aortic valve implantation showed no clear difference in rehospitalisation compared with surgical aortic valve replacement (low certainty).
1 finding from 1 review