Adverse events including extrapyramidal effects · terminally ill adults with delirium
It is very uncertain whether summary of findings: lorazepam changes number of adverse events including extrapyramidal effectsc compared with chlorpromazine (very low certainty).
1 finding from 1 review
Adverse events including extrapyramidal effects · terminally ill adults with delirium
Summary of findings: haloperidol showed no clear difference in adverse events including extrapyramidal effectse compared with placebo (moderate certainty).
1 finding from 1 review
Symptoms of delirium within 24 hoursa · terminally ill adults with delirium
Summary of findings: haloperidol showed no clear difference in symptoms of delirium within 24 hoursa compared with risperidone (low certainty).
1 finding from 1 review
Symptoms of delirium between 24 and 48 hoursa · terminally ill adults with delirium
Summary of findings: haloperidol showed no clear difference in symptoms of delirium between 24 and 48 hoursa compared with risperidone (low certainty).
1 finding from 1 review
Specific behaviour ‐ agitation · terminally ill adults with delirium
The review found no eligible studies for this question.
2 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Participant‐reported pain relief of 30% or greater · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Participant‐reported pain relief of 50% or greater · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Patient Global Impression of Change much or very much improved · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Any pain‐related outcome indicating some improvement · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number experiencing adverse effects · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of participants experiencing any serious adverse events · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Withdrawals due to adverse events · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Pain (PPI‐VAS) · cancer patients
1 finding from 1 review
Anxiety · cancer patients
4 findings from 1 review
no estimate extracted
3 studies · 98 participants
Very low
no estimate extracted
1 study · 30 participants
Very low
no estimate extracted
2 studies · 68 participants
Very low
Show 1 more finding
Anxiety (state) · cancer patients
1 finding from 1 review
Xerostomia (dry mouth relief) · Patients with radiation-induced salivary gland dysfunction
1 finding from 1 review
Johnson 1993: positive response (>25 mm change in VAS score) in 25% of participants on placebo, 51% on pilocarpine 5 mg tds, 47% on pilocarpine 10 mg tds. LeVeque 1993: positive response in 7% on placebo vs 42% on…
2 studies · 278 participants
GRADE not reported
Parasympathomimetic drugs (choline esters, cholinesterase inhibitors) vs No treatment
Outcome not reported · Patients with radiation-induced salivary gland dysfunction
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Other oral symptoms (oral discomfort, dysphonia) · Patients with radiation-induced salivary gland dysfunction
1 finding from 1 review
Both studies assessed oral discomfort and dysphonia (Johnson 1993; LeVeque 1993); pilocarpine reported to improve associated symptoms of salivary gland dysfunction (oral discomfort, dysphonia). No pooled data.
2 studies · 278 participants
GRADE not reported
Salivary flow rate · Patients with radiation-induced salivary gland dysfunction
1 finding from 1 review
Intervention not reported
Chance of obtaining substantial headache relief (Relief). · Acute migraine
The intervention may leads to higher chance of obtaining substantial headache relief (Relief). (low certainty).
1 finding from 1 review