Acceptability Proportion satisfied with treatment · heavy menstrual bleeding
Endometrial resection/ablation showed no clear difference in acceptability Proportion satisfied with treatment compared with unspecified (or at surgeon's discretion) route of hysterectomy (moderate certainty).
1 finding from 1 review
Safety Any serious adverse event · heavy menstrual bleeding
Endometrial resection/ablation probably leads to lower safety Any serious adverse event compared with unspecified (or at surgeon's discretion) route of hysterectomy (moderate certainty).
1 finding from 1 review
Return to normal activity · heavy menstrual bleeding
1 finding from 1 review
Effectiveness Proportion of women with perception of improvement of bleeding symptoms · HMB
Endometrial resection or ablation probably leads to lower effectiveness Woman's perception (proportion with improvement in… compared with open hysterectomy (moderate certainty).
1 finding from 1 review
Acceptability Proportion satisfied with treatment · heavy menstrual bleeding
Endometrial resection or ablation probably leads to lower acceptability Proportion satisfied with treatment compared with minimally invasive hysterectomy (moderate certainty).
1 finding from 1 review
Safety Any serious adverse event · heavy menstrual bleeding
Endometrial resection or ablation showed no clear difference in safety Any serious adverse event compared with minimally invasive hysterectomy (moderate certainty).
1 finding from 1 review
Return to normal activity · heavy menstrual bleeding
1 finding from 1 review
no estimate extracted
99 participants
GRADE not reported
Quality of life SF‐36 at 2 years – general health perception · HMB
1 finding from 1 review
Requirement for further surgery for treatment failure within 1 year after surgery · HMB
1 finding from 1 review
Acceptability Proportion satisfied with treatment · HMB
Endometrial resection or ablation showed no clear difference in acceptability Proportion satisfied with treatment compared with open hysterectomy (moderate certainty).
1 finding from 1 review
Safety Any serious adverse event · HMB
Endometrial resection or ablation showed no clear difference in safety Any serious adverse events compared with open hysterectomy (low certainty).
1 finding from 1 review
Return to normal activity · HMB
1 finding from 1 review
Effectiveness · heavy menstrual bleeding
Endometrial resection or ablation showed no clear difference in effectiveness compared with minimally invasive hysterectomy (low certainty).
1 finding from 1 review
Quality of life · heavy menstrual bleeding
1 finding from 1 review
Requirement for further surgery for treatment failure within 1 year after surgery · heavy menstrual bleeding
Endometrial resection or ablation probably leads to higher requirement for further surgery for treatment failure within 1 year… compared with minimally invasive hysterectomy (moderate certainty).
1 finding from 1 review
Miscarriage · women with polycystic ovary syndrome
Metformin combined with clomiphene citrate showed no clear difference in miscarriage rate per woman compared with clomiphene citrate alone (low certainty).
Live birth rate per woman · women with polycystic ovary syndrome
Metformin combined with clomiphene citrate showed no clear difference in live birth rate per woman compared with clomiphene citrate alone (low certainty).
Gastrointestinal adverse events · women with polycystic ovary syndrome
Metformin combined with clomiphene citrate probably leads to higher adverse events (gastrointestinal) per woman compared with clomiphene citrate alone (moderate certainty).
Clinical pregnancy rate · women with polycystic ovary syndrome
Metformin combined with clomiphene citrate probably leads to higher clinical pregnancy rate per woman compared with clomiphene citrate alone (moderate certainty).
Ovulation rate · women with polycystic ovary syndrome
Metformin combined with clomiphene citrate may leads to higher ovulation rate per woman compared with clomiphene citrate alone (low certainty).