Metformin combined with clomiphene citrate vs clomiphene: Ovulation rate
- Population
- women with polycystic ovary syndrome
- Intervention
- Metformin combined with clomiphene citrate
- Comparison
- clomiphene
- Outcome
- Ovulation rate
Reviews word the same question differently. Two decision models (TypeSafe's Jev and Liquid AI's d1) judged each wording of the population, intervention, comparator and outcome against the others, and rows count as this question only when both agree on all four. Timing, setting and subgroup never split a question: they are shown on each row.
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
How each review answered it
Include earlier review versions| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Metformin combined with clomiphene citrate vs clomiphene citrate alone Ovulation rate per woman · women with polycystic ovary syndrome Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome (2019) · Cochrane | OR 1.65 [1.35, 2.03] | 22 studies · 1601 participants | Low |
Metformin combined with clomiphene citrate vs clomiphene citrate alone Ovulation rate per woman · women with polycystic ovary syndrome Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with… (2017) · Cochrane | OR 1.57 [1.28, 1.92] | 21 studies · 1624 participants | Moderate |
Trials and studies behind the answers
The primary studies that full-text reviews tie to these outcomes. Reviews from the Summary of Findings tier list no included studies here, and trials have not yet been matched to questions on their own, so this list is incomplete.